3-Hydroxyglibenclamide
TL;DR: 3-Hydroxyglibenclamide (CAS 1217848-91-3) is a chemical compound with molecular formula C23H28ClN3O6S and molecular weight 509.14 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
5-chloro-N-[2-[4-[(3-hydroxycyclohexyl)carbamoylsulfamoyl]phenyl]ethyl]-2-methoxybenzamide
Also Known As: 3-Hydroxyglibenclamide, cis-3-Hydroxyglyburide, raccis-3-HydroxyGlyburide, 3-cis-Hydroxyglibenclamide, rac cis-3-Hydroxy Glyburide
| Molecular Formula | C23H28ClN3O6S |
|---|---|
| Molecular Weight | 509.14 g/mol |
| LogP | 2.6125 |
| Topological Polar Surface Area | 133.83 Ų |
| Hydrogen Bond Donors | 4 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 8 |
| Exact Mass | 509.13873 |
| Heavy Atoms | 34 |
| Complexity | 1124.0254 |
Chemical Identifiers
| CAS Number | 1217848-91-3 |
|---|---|
| SMILES | COC1=C(C=C(C=C1)Cl)C(=O)NCCC2=CC=C(C=C2)S(=O)(=O)NC(=O)NC3CCCC(C3)O |
Product Overview
3-Hydroxyglibenclamide (CAS 1217848-91-3), with molecular formula C23H28ClN3O6S and molecular weight 509.14 g/mol. IUPAC: 5-chloro-N-[2-[4-[(3-hydroxycyclohexyl)carbamoylsulfamoyl]phenyl]ethyl]-2-methoxybenzamide.
Chemical Property Profile of 3-Hydroxyglibenclamide
Property Insights of 3-Hydroxyglibenclamide
The XLogP value of 2.6125 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 3-Hydroxyglibenclamide. The TPSA of 133.83 Ų falls within the moderate polarity range, balancing permeability and solubility for 3-Hydroxyglibenclamide. Following Lipinski's Rule of Five, 3-Hydroxyglibenclamide has 4 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 3-Hydroxyglibenclamide?
The CAS number of 3-Hydroxyglibenclamide is 1217848-91-3.
What is the molecular formula of 3-Hydroxyglibenclamide?
The molecular formula of 3-Hydroxyglibenclamide is C23H28ClN3O6S.
What is the molecular weight of 3-Hydroxyglibenclamide?
The molecular weight of 3-Hydroxyglibenclamide is 509.14 g/mol.
Where can I buy 3-Hydroxyglibenclamide?
You can request a quote for 3-Hydroxyglibenclamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 3-Hydroxyglibenclamide?
Yes, KEHONG BIO provides custom synthesis services for 3-Hydroxyglibenclamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.