Boc-(S)-alpha-(4-thiazolylmethyl)-proline structure

Boc-(S)-alpha-(4-thiazolylmethyl)-proline

TL;DR: Boc-(S)-alpha-(4-thiazolylmethyl)-proline (CAS 1217628-22-2) is a chemical compound with molecular formula C14H20N2O4S and molecular weight 312.11 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

(2S)-1-[(2-methylpropan-2-yl)oxycarbonyl]-2-(1,3-thiazol-4-ylmethyl)pyrrolidine-2-carboxylic acid

Also Known As: Boc-(S)-alpha-(4-thiazolylmethyl)-proline, Boc-D-(4-ThzMe)Pro-OH, BOC-(S)-A-(4-THIAZOLYLMETHYL)PROLINE, N-(t-Butoxycarbonyl)-2-(4-thiazolylmethyl)-D-proline, (2S)-1-[(2-methylpropan-2-yl)oxycarbonyl]-2-(1,3-thiazol-4-ylmethyl)pyrrolidine-2-carboxylic acid

CAS: 1217628-22-2
Molecular Formula C14H20N2O4S
Molecular Weight 312.11 g/mol
LogP 2.5399
Topological Polar Surface Area 79.73 Ų
Hydrogen Bond Donors 1
Hydrogen Bond Acceptors 5
Rotatable Bonds 3
Exact Mass 312.11438
Heavy Atoms 21
Complexity 523.57635

Chemical Identifiers

CAS Number 1217628-22-2
SMILES CC(C)(C)OC(=O)N1CCC[C@]1(CC2=CSC=N2)C(=O)O

Product Overview

Boc-(S)-alpha-(4-thiazolylmethyl)-proline (CAS 1217628-22-2), with molecular formula C14H20N2O4S and molecular weight 312.11 g/mol. IUPAC: (2S)-1-[(2-methylpropan-2-yl)oxycarbonyl]-2-(1,3-thiazol-4-ylmethyl)pyrrolidine-2-carboxylic acid.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
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Chemical Property Profile of Boc-(S)-alpha-(4-thiazolylmethyl)-proline

XLogP
2.5399
TPSA (Topological Polar Surface Area)
79.73
Hydrogen Bond Donors
1
Hydrogen Bond Acceptors
5
Rotatable Bonds
3
Heavy Atoms
21
Complexity
523.57635
Exact Mass
312.11438
Monoisotopic Mass
312.11438
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Boc-(S)-alpha-(4-thiazolylmethyl)-proline

The XLogP value of 2.5399 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Boc-(S)-alpha-(4-thiazolylmethyl)-proline. The TPSA of 79.73 Ų falls within the moderate polarity range, balancing permeability and solubility for Boc-(S)-alpha-(4-thiazolylmethyl)-proline. Following Lipinski's Rule of Five, Boc-(S)-alpha-(4-thiazolylmethyl)-proline has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Boc-(S)-alpha-(4-thiazolylmethyl)-proline?

The CAS number of Boc-(S)-alpha-(4-thiazolylmethyl)-proline is 1217628-22-2.

What is the molecular formula of Boc-(S)-alpha-(4-thiazolylmethyl)-proline?

The molecular formula of Boc-(S)-alpha-(4-thiazolylmethyl)-proline is C14H20N2O4S.

What is the molecular weight of Boc-(S)-alpha-(4-thiazolylmethyl)-proline?

The molecular weight of Boc-(S)-alpha-(4-thiazolylmethyl)-proline is 312.11 g/mol.

Where can I buy Boc-(S)-alpha-(4-thiazolylmethyl)-proline?

You can request a quote for Boc-(S)-alpha-(4-thiazolylmethyl)-proline directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Boc-(S)-alpha-(4-thiazolylmethyl)-proline?

Yes, KEHONG BIO provides custom synthesis services for Boc-(S)-alpha-(4-thiazolylmethyl)-proline and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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