Fti 277
TL;DR: Fti 277 (CAS 1217447-06-7) is a chemical compound with molecular formula C22H29N3O3S2 and molecular weight 447.17 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
methyl (2S)-2-[[4-[[(2R)-2-amino-3-sulfanylpropyl]amino]-2-phenylbenzoyl]amino]-4-methylsulfanylbutanoate
Also Known As: FTI-277 trifluoroacetate salt, SID:53790241, methyl (2S)-2-[[4-[[(2R)-2-amino-3-sulfanylpropyl]amino]-2-phenylbenzoyl]amino]-4-methylsulfanylbutanoate, methyl (5-(((R)-2-amino-3-mercaptopropyl)amino)-[1,1'-biphenyl]-2-carbonyl)-L-methioninate, Methyl {N-[2-phenyl-4-N [2(R)-amino-3-mecaptopropylamino] benzoyl]}-methionate, TFA
| Molecular Formula | C22H29N3O3S2 |
|---|---|
| Molecular Weight | 447.17 g/mol |
| LogP | 3.0471 |
| Topological Polar Surface Area | 93.45 Ų |
| Hydrogen Bond Donors | 4 |
| Hydrogen Bond Acceptors | 7 |
| Rotatable Bonds | 11 |
| Exact Mass | 447.16504 |
| Heavy Atoms | 30 |
| Complexity | 833.6324 |
Chemical Identifiers
| CAS Number | 1217447-06-7 |
|---|---|
| SMILES | COC(=O)[C@H](CCSC)NC(=O)C1=C(C=C(C=C1)NC[C@H](CS)N)C2=CC=CC=C2 |
Product Overview
Fti 277 (CAS 1217447-06-7), with molecular formula C22H29N3O3S2 and molecular weight 447.17 g/mol. IUPAC: methyl (2S)-2-[[4-[[(2R)-2-amino-3-sulfanylpropyl]amino]-2-phenylbenzoyl]amino]-4-methylsulfanylbutanoate.
Chemical Property Profile of Fti 277
Property Insights of Fti 277
The XLogP value of 3.0471 indicates that Fti 277 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 93.45 Ų falls within the moderate polarity range, balancing permeability and solubility for Fti 277. Following Lipinski's Rule of Five, Fti 277 has 4 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Fti 277?
The CAS number of Fti 277 is 1217447-06-7.
What is the molecular formula of Fti 277?
The molecular formula of Fti 277 is C22H29N3O3S2.
What is the molecular weight of Fti 277?
The molecular weight of Fti 277 is 447.17 g/mol.
Where can I buy Fti 277?
You can request a quote for Fti 277 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Fti 277?
Yes, KEHONG BIO provides custom synthesis services for Fti 277 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.