![(1R,5S)-3-(2-((4-hydroxy-5-isopentyl-6-oxo-1,6-dihydropyrimidin-2-yl)thio)acetyl)-3,4,5,6-tetrahydro-1H-1,5-methanopyrido[1,2-a][1,5]diazocin-8(2H)-one structure](/static/products/121/1212360-99-0.png)
(1R,5S)-3-(2-((4-hydroxy-5-isopentyl-6-oxo-1,6-dihydropyrimidin-2-yl)thio)acetyl)-3,4,5,6-tetrahydro-1H-1,5-methanopyrido[1,2-a][1,5]diazocin-8(2H)-one
概要：(1R,5S)-3-(2-((4-hydroxy-5-isopentyl-6-oxo-1,6-dihydropyrimidin-2-yl)thio)acetyl)-3,4,5,6-tetrahydro-1H-1,5-methanopyrido[1,2-a][1,5]diazocin-8(2H)-one（CAS 1212360-99-0）是一种化学化合物，分子式为C22H28N4O4S，分子量为444.18 g/mol。河南科弘生物科技有限公司提供CRO/CDMO定制合成服务，支持克级到吨级规格。
(1S,9S)-11-[2-[[4-hydroxy-5-(3-methylbutyl)-6-oxo-1H-pyrimidin-2-yl]sulfanyl]acetyl]-7,11-diazatricyclo[7.3.1.02,7]trideca-2,4-dien-6-one
又称：(1R,5S)-3-(2-((4-hydroxy-5-isopentyl-6-oxo-1,6-dihydropyrimidin-2-yl)thio)acetyl)-3,4,5,6-tetrahydro-1H-1,5-methanopyrido[1,2-a][1,5]diazocin-8(2H)-one
| 分子式 | C22H28N4O4S |
|---|---|
| 分子量 | 444.18 g/mol |
| LogP | 1.9638 |
| 拓扑极性表面积 | 108.29 Ų |
| 氢键供体数 | 2 |
| 氢键受体数 | 6 |
| 可旋转键数 | 6 |
| 精确质量 | 444.18314 |
| 重原子数 | 31 |
| 复杂度 | 1093.6489 |
化学标识符
| CAS 编号 | 1212360-99-0 |
|---|---|
| SMILES | CC(C)CCC1=C(N=C(NC1=O)SCC(=O)N2C[C@@H]3C[C@@H](C2)C4=CC=CC(=O)N4C3)O |
产品概述
(1R,5S)-3-(2-((4-hydroxy-5-isopentyl-6-oxo-1,6-dihydropyrimidin-2-yl)thio)acetyl)-3,4,5,6-tetrahydro-1H-1,5-methanopyrido[1,2-a][1,5]diazocin-8(2H)-one（CAS 1212360-99-0），分子式为C22H28N4O4S，分子量为444.18 g/mol。IUPAC名：(1S,9S)-11-[2-[[4-hydroxy-5-(3-methylbutyl)-6-oxo-1H-pyrimidin-2-yl]sulfanyl]acetyl]-7,11-diazatricyclo[7.3.1.02,7]trideca-2,4-dien-6-one。
(1R,5S)-3-(2-((4-hydroxy-5-isopentyl-6-oxo-1,6-dihydropyrimidin-2-yl)thio)acetyl)-3,4,5,6-tetrahydro-1H-1,5-methanopyrido[1,2-a][1,5]diazocin-8(2H)-one化学性质概览
属性洞察：(1R,5S)-3-(2-((4-hydroxy-5-isopentyl-6-oxo-1,6-dihydropyrimidin-2-yl)thio)acetyl)-3,4,5,6-tetrahydro-1H-1,5-methanopyrido[1,2-a][1,5]diazocin-8(2H)-one
(1R,5S)-3-(2-((4-hydroxy-5-isopentyl-6-oxo-1,6-dihydropyrimidin-2-yl)thio)acetyl)-3,4,5,6-tetrahydro-1H-1,5-methanopyrido[1,2-a][1,5]diazocin-8(2H)-one的XLogP值为1.9638，表明具有中等亲脂性，在水溶性和膜透过性之间取得平衡。 TPSA为108.29 Ų，处于中等极性范围，在透过性和溶解性之间取得平衡。 根据Lipinski五规则，(1R,5S)-3-(2-((4-hydroxy-5-isopentyl-6-oxo-1,6-dihydropyrimidin-2-yl)thio)acetyl)-3,4,5,6-tetrahydro-1H-1,5-methanopyrido[1,2-a][1,5]diazocin-8(2H)-one有2个氢键供体和6个氢键受体，均在类药范围内，提示具有较好的口服生物利用度潜力。
常见问题
常见问题
(1R,5S)-3-(2-((4-hydroxy-5-isopentyl-6-oxo-1,6-dihydropyrimidin-2-yl)thio)acetyl)-3,4,5,6-tetrahydro-1H-1,5-methanopyrido[1,2-a][1,5]diazocin-8(2H)-one的CAS号是多少？
(1R,5S)-3-(2-((4-hydroxy-5-isopentyl-6-oxo-1,6-dihydropyrimidin-2-yl)thio)acetyl)-3,4,5,6-tetrahydro-1H-1,5-methanopyrido[1,2-a][1,5]diazocin-8(2H)-one的CAS号为1212360-99-0。
(1R,5S)-3-(2-((4-hydroxy-5-isopentyl-6-oxo-1,6-dihydropyrimidin-2-yl)thio)acetyl)-3,4,5,6-tetrahydro-1H-1,5-methanopyrido[1,2-a][1,5]diazocin-8(2H)-one的分子式是什么？
(1R,5S)-3-(2-((4-hydroxy-5-isopentyl-6-oxo-1,6-dihydropyrimidin-2-yl)thio)acetyl)-3,4,5,6-tetrahydro-1H-1,5-methanopyrido[1,2-a][1,5]diazocin-8(2H)-one的分子式为C22H28N4O4S。
(1R,5S)-3-(2-((4-hydroxy-5-isopentyl-6-oxo-1,6-dihydropyrimidin-2-yl)thio)acetyl)-3,4,5,6-tetrahydro-1H-1,5-methanopyrido[1,2-a][1,5]diazocin-8(2H)-one的分子量是多少？
(1R,5S)-3-(2-((4-hydroxy-5-isopentyl-6-oxo-1,6-dihydropyrimidin-2-yl)thio)acetyl)-3,4,5,6-tetrahydro-1H-1,5-methanopyrido[1,2-a][1,5]diazocin-8(2H)-one的分子量为444.18 g/mol。
在哪里可以购买(1R,5S)-3-(2-((4-hydroxy-5-isopentyl-6-oxo-1,6-dihydropyrimidin-2-yl)thio)acetyl)-3,4,5,6-tetrahydro-1H-1,5-methanopyrido[1,2-a][1,5]diazocin-8(2H)-one？
您可以直接向科弘生物询价(1R,5S)-3-(2-((4-hydroxy-5-isopentyl-6-oxo-1,6-dihydropyrimidin-2-yl)thio)acetyl)-3,4,5,6-tetrahydro-1H-1,5-methanopyrido[1,2-a][1,5]diazocin-8(2H)-one。联系我们或发送邮件至info@kehongbio.com获取报价和库存信息。
科弘生物是否提供(1R,5S)-3-(2-((4-hydroxy-5-isopentyl-6-oxo-1,6-dihydropyrimidin-2-yl)thio)acetyl)-3,4,5,6-tetrahydro-1H-1,5-methanopyrido[1,2-a][1,5]diazocin-8(2H)-one的定制合成服务？
是的，科弘生物提供(1R,5S)-3-(2-((4-hydroxy-5-isopentyl-6-oxo-1,6-dihydropyrimidin-2-yl)thio)acetyl)-3,4,5,6-tetrahydro-1H-1,5-methanopyrido[1,2-a][1,5]diazocin-8(2H)-one及相关化合物的定制合成服务。请联系我们并告知您的具体需求，包括数量、纯度和交期。