Amphocil
TL;DR: Amphocil (CAS 120895-52-5) is a chemical compound with molecular formula C74H119NO21S and molecular weight 1389.80 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(1R,3S,5R,6R,9R,11R,15S,16R,17R,18S,19E,21E,23E,25E,27E,29E,31E,33R,35S,36R,37S)-33-[(2R,3S,4S,5S,6R)-4-amino-3,5-dihydroxy-6-methyloxan-2-yl]oxy-1,3,5,6,9,11,17,37-octahydroxy-15,16,18-trimethyl-13-oxo-14,39-dioxabicyclo[33.3.1]nonatriaconta-19,21,23,25,27,29,31-heptaene-36-carboxylic acid;[(3S,8S,9S,10R,13R,14S,17R)-10,13-dimethyl-17-[(2R)-6-methylheptan-2-yl]-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl] hydrogen sulfate
Also Known As: Amphocil, ABCD, Amphotericin B cholesteryl sulfate, Compd with cholesteryl sulfate, AMPHOTERICIN B CHOLESTERYL SULFATE COMPLEX
| Molecular Formula | C74H119NO21S |
|---|---|
| Molecular Weight | 1389.80 g/mol |
| LogP | 7.9275 |
| Topological Polar Surface Area | 383.21 Ų |
| Hydrogen Bond Donors | 13 |
| Hydrogen Bond Acceptors | 20 |
| Rotatable Bonds | 10 |
| Exact Mass | 1389.7996 |
| Heavy Atoms | 97 |
| Complexity | 2840.992 |
Chemical Identifiers
| CAS Number | 120895-52-5 |
|---|---|
| SMILES | C[C@H]1/C=C/C=C/C=C/C=C/C=C/C=C/C=C/[C@@H](C[C@H]2[C@@H]([C@H](C[C@](O2)(C[C@H](C[C@H]([C@@H](CC[C@H](C[C@H](CC(=O)O[C@H]([C@@H]([C@@H]1O)C)C)O)O)O)O)O)O)O)C(=O)O)O[C@H]3[C@H]([C@H]([C@@H]([C@H](O3)C)O)N)O.C[C@H](CCCC(C)C)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CC=C4[C@@]3(CC[C@@H](C4)OS(=O)(=O)O)C)C |
Product Overview
Amphocil (CAS 120895-52-5), with molecular formula C74H119NO21S and molecular weight 1389.80 g/mol. IUPAC: (1R,3S,5R,6R,9R,11R,15S,16R,17R,18S,19E,21E,23E,25E,27E,29E,31E,33R,35S,36R,37S)-33-[(2R,3S,4S,5S,6R)-4-amino-3,5-dihydroxy-6-methyloxan-2-yl]oxy-1,3,5,6,9,11,17,37-octahydroxy-15,16,18-trimethyl-13-oxo-14,39-dioxabicyclo[33.3.1]nonatriaconta-19,21,23,25,27,29,31-heptaene-36-carboxylic acid;[(3S,8S,9S,10R,13R,14S,17R)-10,13-dimethyl-17-[(2R)-6-methylheptan-2-yl]-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl] hydrogen sulfate.
Chemical Property Profile of Amphocil
Property Insights of Amphocil
The XLogP value of 7.9275 indicates that Amphocil is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 383.21 Ų indicates high polarity, suggesting Amphocil may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Amphocil has 13 hydrogen bond donor(s) and 20 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Amphocil?
The CAS number of Amphocil is 120895-52-5.
What is the molecular formula of Amphocil?
The molecular formula of Amphocil is C74H119NO21S.
What is the molecular weight of Amphocil?
The molecular weight of Amphocil is 1389.80 g/mol.
Where can I buy Amphocil?
You can request a quote for Amphocil directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Amphocil?
Yes, KEHONG BIO provides custom synthesis services for Amphocil and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.