Midostaurin; 4'-N-benzoylstaurosporine
TL;DR: Midostaurin; 4'-N-benzoylstaurosporine (CAS 120685-11-2) is a chemical compound with molecular formula C35H30N4O4 and molecular weight 570.23 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-[(15R,16S,17R,18S)-17-methoxy-17,18-dimethyl-5-oxo-28-oxa-4,14,19-triazaoctacyclo[12.11.2.115,18.02,6.07,27.08,13.019,26.020,25]octacosa-1,6,8,10,12,20,22,24,26-nonaen-16-yl]-N-methylbenzamide
Also Known As: Midostaurin, Benzoylstaurosporine, Midostaurin [INN], 4'-N-Benzoylstaurosporine, Midostaurin (PKC412)
| Molecular Formula | C35H30N4O4 |
|---|---|
| Molecular Weight | 570.23 g/mol |
| LogP | 4.7 |
| Topological Polar Surface Area | 77.7 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 3 |
| Exact Mass | 570.2267 |
| Heavy Atoms | 43 |
| Complexity | 1180.0 |
Chemical Identifiers
| CAS Number | 120685-11-2 |
|---|---|
| SMILES | C[C@]1([C@@H]([C@@H]2N3C4=CC=CC=C4C5=C6C(=C7C8=CC=CC=C8N(C7=C53)[C@]1(O2)C)CNC6=O)N(C)C(=O)C9=CC=CC=C9)OC |
| InChIKey | IIQIEMHSDLLZQA-QZPVEUDVSA-N |
Product Overview
Midostaurin; 4'-N-benzoylstaurosporine (CAS 120685-11-2), with molecular formula C35H30N4O4 and molecular weight 570.23 g/mol. IUPAC: N-[(15R,16S,17R,18S)-17-methoxy-17,18-dimethyl-5-oxo-28-oxa-4,14,19-triazaoctacyclo[12.11.2.115,18.02,6.07,27.08,13.019,26.020,25]octacosa-1,6,8,10,12,20,22,24,26-nonaen-16-yl]-N-methylbenzamide.
Chemical Property Profile of Midostaurin; 4'-N-benzoylstaurosporine
Property Insights of Midostaurin; 4'-N-benzoylstaurosporine
The XLogP value of 4.7 indicates that Midostaurin; 4'-N-benzoylstaurosporine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 77.7 Ų falls within the moderate polarity range, balancing permeability and solubility for Midostaurin; 4'-N-benzoylstaurosporine. Following Lipinski's Rule of Five, Midostaurin; 4'-N-benzoylstaurosporine has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Midostaurin; 4'-N-benzoylstaurosporine?
The CAS number of Midostaurin; 4'-N-benzoylstaurosporine is 120685-11-2.
What is the molecular formula of Midostaurin; 4'-N-benzoylstaurosporine?
The molecular formula of Midostaurin; 4'-N-benzoylstaurosporine is C35H30N4O4.
What is the molecular weight of Midostaurin; 4'-N-benzoylstaurosporine?
The molecular weight of Midostaurin; 4'-N-benzoylstaurosporine is 570.23 g/mol.
Where can I buy Midostaurin; 4'-N-benzoylstaurosporine?
You can request a quote for Midostaurin; 4'-N-benzoylstaurosporine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Midostaurin; 4'-N-benzoylstaurosporine?
Yes, KEHONG BIO provides custom synthesis services for Midostaurin; 4'-N-benzoylstaurosporine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.