3'-Azido-5'-O-tert-butyldimethylsilyl-3'-deoxythymidine
TL;DR: 3'-Azido-5'-O-tert-butyldimethylsilyl-3'-deoxythymidine (CAS 120624-97-7) is a chemical compound with molecular formula C16H27N5O4Si and molecular weight 381.18 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1-[4-azido-5-[[tert-butyl(dimethyl)silyl]oxymethyl]oxolan-2-yl]-5-methylpyrimidine-2,4-dione
Also Known As: NCI60_029670, 3'-Azido-5'-O-tert-butyldimethylsilyl-3'-deoxythymidine, 10.14272/CXIAWCOBGBHOCC-UHFFFAOYSA-N, doi:10.14272/CXIAWCOBGBHOCC-UHFFFAOYSA-N, Thymidine, 3'-azido-3'-deoxy-5'-O-[(1,1-dimethylethyl)dimethylsilyl]-
| Molecular Formula | C16H27N5O4Si |
|---|---|
| Molecular Weight | 381.18 g/mol |
| LogP | 2.83322 |
| Topological Polar Surface Area | 82.2 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 6 |
| Exact Mass | 381.18323 |
| Heavy Atoms | 26 |
| Complexity | 666.0 |
Chemical Identifiers
| CAS Number | 120624-97-7 |
|---|---|
| SMILES | CC1=CN(C(=O)NC1=O)C2CC(C(O2)CO[Si](C)(C)C(C)(C)C)N=[N+]=[N-] |
| InChIKey | CXIAWCOBGBHOCC-UHFFFAOYSA-N |
Product Overview
3'-Azido-5'-O-tert-butyldimethylsilyl-3'-deoxythymidine (CAS 120624-97-7), with molecular formula C16H27N5O4Si and molecular weight 381.18 g/mol. IUPAC: 1-[4-azido-5-[[tert-butyl(dimethyl)silyl]oxymethyl]oxolan-2-yl]-5-methylpyrimidine-2,4-dione.
Chemical Property Profile of 3'-Azido-5'-O-tert-butyldimethylsilyl-3'-deoxythymidine
Property Insights of 3'-Azido-5'-O-tert-butyldimethylsilyl-3'-deoxythymidine
The XLogP value of 2.83322 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 3'-Azido-5'-O-tert-butyldimethylsilyl-3'-deoxythymidine. The TPSA of 82.2 Ų falls within the moderate polarity range, balancing permeability and solubility for 3'-Azido-5'-O-tert-butyldimethylsilyl-3'-deoxythymidine. Following Lipinski's Rule of Five, 3'-Azido-5'-O-tert-butyldimethylsilyl-3'-deoxythymidine has 1 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 3'-Azido-5'-O-tert-butyldimethylsilyl-3'-deoxythymidine?
The CAS number of 3'-Azido-5'-O-tert-butyldimethylsilyl-3'-deoxythymidine is 120624-97-7.
What is the molecular formula of 3'-Azido-5'-O-tert-butyldimethylsilyl-3'-deoxythymidine?
The molecular formula of 3'-Azido-5'-O-tert-butyldimethylsilyl-3'-deoxythymidine is C16H27N5O4Si.
What is the molecular weight of 3'-Azido-5'-O-tert-butyldimethylsilyl-3'-deoxythymidine?
The molecular weight of 3'-Azido-5'-O-tert-butyldimethylsilyl-3'-deoxythymidine is 381.18 g/mol.
Where can I buy 3'-Azido-5'-O-tert-butyldimethylsilyl-3'-deoxythymidine?
You can request a quote for 3'-Azido-5'-O-tert-butyldimethylsilyl-3'-deoxythymidine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 3'-Azido-5'-O-tert-butyldimethylsilyl-3'-deoxythymidine?
Yes, KEHONG BIO provides custom synthesis services for 3'-Azido-5'-O-tert-butyldimethylsilyl-3'-deoxythymidine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.