2-Amino-4-(4-chlorophenyl)-6-(2-thienyl)nicotinonitrile
TL;DR: 2-Amino-4-(4-chlorophenyl)-6-(2-thienyl)nicotinonitrile (CAS 120239-03-4) is a chemical compound with molecular formula C16H10ClN3S and molecular weight 311.03 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-amino-4-(4-chlorophenyl)-6-thiophen-2-ylpyridine-3-carbonitrile
Also Known As: 6H-358S, 2-amino-4-(4-chlorophenyl)-6-(2-thienyl)nicotinonitrile, 2-amino-4-(4-chlorophenyl)-6-thiophen-2-ylpyridine-3-carbonitrile, 2-amino-4-(4-chlorophenyl)-6-(thiophen-2-yl)pyridine-3-carbonitrile, 2-amino-4-(4-chlorophenyl)-6-(thien-2-yl)nicotinonitrile
| Molecular Formula | C16H10ClN3S |
|---|---|
| Molecular Weight | 311.03 g/mol |
| LogP | 4.58438 |
| Topological Polar Surface Area | 62.7 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 2 |
| Exact Mass | 311.02838 |
| Heavy Atoms | 21 |
| Complexity | 817.9736 |
Chemical Identifiers
| CAS Number | 120239-03-4 |
|---|---|
| SMILES | C1=CSC(=C1)C2=NC(=C(C(=C2)C3=CC=C(C=C3)Cl)C#N)N |
Product Overview
2-Amino-4-(4-chlorophenyl)-6-(2-thienyl)nicotinonitrile (CAS 120239-03-4), with molecular formula C16H10ClN3S and molecular weight 311.03 g/mol. IUPAC: 2-amino-4-(4-chlorophenyl)-6-thiophen-2-ylpyridine-3-carbonitrile.
Chemical Property Profile of 2-Amino-4-(4-chlorophenyl)-6-(2-thienyl)nicotinonitrile
Property Insights of 2-Amino-4-(4-chlorophenyl)-6-(2-thienyl)nicotinonitrile
The XLogP value of 4.58438 indicates that 2-Amino-4-(4-chlorophenyl)-6-(2-thienyl)nicotinonitrile is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 62.7 Ų falls within the moderate polarity range, balancing permeability and solubility for 2-Amino-4-(4-chlorophenyl)-6-(2-thienyl)nicotinonitrile. Following Lipinski's Rule of Five, 2-Amino-4-(4-chlorophenyl)-6-(2-thienyl)nicotinonitrile has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 2-Amino-4-(4-chlorophenyl)-6-(2-thienyl)nicotinonitrile?
The CAS number of 2-Amino-4-(4-chlorophenyl)-6-(2-thienyl)nicotinonitrile is 120239-03-4.
What is the molecular formula of 2-Amino-4-(4-chlorophenyl)-6-(2-thienyl)nicotinonitrile?
The molecular formula of 2-Amino-4-(4-chlorophenyl)-6-(2-thienyl)nicotinonitrile is C16H10ClN3S.
What is the molecular weight of 2-Amino-4-(4-chlorophenyl)-6-(2-thienyl)nicotinonitrile?
The molecular weight of 2-Amino-4-(4-chlorophenyl)-6-(2-thienyl)nicotinonitrile is 311.03 g/mol.
Where can I buy 2-Amino-4-(4-chlorophenyl)-6-(2-thienyl)nicotinonitrile?
You can request a quote for 2-Amino-4-(4-chlorophenyl)-6-(2-thienyl)nicotinonitrile directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 2-Amino-4-(4-chlorophenyl)-6-(2-thienyl)nicotinonitrile?
Yes, KEHONG BIO provides custom synthesis services for 2-Amino-4-(4-chlorophenyl)-6-(2-thienyl)nicotinonitrile and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.