3 -Allyl-5 -O-(tert-butyldimethylsilyl)-3 -deoxythymidine
TL;DR: 3 -Allyl-5 -O-(tert-butyldimethylsilyl)-3 -deoxythymidine (CAS 120232-08-8) is a chemical compound with molecular formula C19H32N2O4Si and molecular weight 380.21 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1-[(2R,4S,5S)-5-[[tert-butyl(dimethyl)silyl]oxymethyl]-4-prop-2-enyloxolan-2-yl]-5-methylpyrimidine-2,4-dione
Also Known As: 3 -Allyl-5 -O-(tert-butyldimethylsilyl)-3 -deoxythymidine, 3 -Deoxy-3 -allyl-5 -O-(tert-butyldimethylsilyl)thymidine, 3'-Deoxy-5'-O-[(1,1-dimethylethyl)dimethylsilyl]-3'-(2-propen-1-yl)thymidine, 1-[(2R,4S,5S)-4-allyl-5-[[tert-butyl(dimethyl)silyl]oxymethyl]tetrahydrofuran-2-yl]-5-methyl-pyrimidine-2,4-dione, 1-[(2R,4S,5S)-5-[[tert-butyl(dimethyl)silyl]oxymethyl]-4-prop-2-enyloxolan-2-yl]-5-methylpyrimidine-2,4-dione
| Molecular Formula | C19H32N2O4Si |
|---|---|
| Molecular Weight | 380.21 g/mol |
| LogP | 3.34662 |
| Topological Polar Surface Area | 73.32 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 6 |
| Exact Mass | 380.21313 |
| Heavy Atoms | 26 |
| Complexity | 760.02826 |
Chemical Identifiers
| CAS Number | 120232-08-8 |
|---|---|
| SMILES | CC1=CN(C(=O)NC1=O)[C@H]2C[C@@H]([C@H](O2)CO[Si](C)(C)C(C)(C)C)CC=C |
Product Overview
3 -Allyl-5 -O-(tert-butyldimethylsilyl)-3 -deoxythymidine (CAS 120232-08-8), with molecular formula C19H32N2O4Si and molecular weight 380.21 g/mol. IUPAC: 1-[(2R,4S,5S)-5-[[tert-butyl(dimethyl)silyl]oxymethyl]-4-prop-2-enyloxolan-2-yl]-5-methylpyrimidine-2,4-dione.
Chemical Property Profile of 3 -Allyl-5 -O-(tert-butyldimethylsilyl)-3 -deoxythymidine
Property Insights of 3 -Allyl-5 -O-(tert-butyldimethylsilyl)-3 -deoxythymidine
The XLogP value of 3.34662 indicates that 3 -Allyl-5 -O-(tert-butyldimethylsilyl)-3 -deoxythymidine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 73.32 Ų falls within the moderate polarity range, balancing permeability and solubility for 3 -Allyl-5 -O-(tert-butyldimethylsilyl)-3 -deoxythymidine. Following Lipinski's Rule of Five, 3 -Allyl-5 -O-(tert-butyldimethylsilyl)-3 -deoxythymidine has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 3 -Allyl-5 -O-(tert-butyldimethylsilyl)-3 -deoxythymidine?
The CAS number of 3 -Allyl-5 -O-(tert-butyldimethylsilyl)-3 -deoxythymidine is 120232-08-8.
What is the molecular formula of 3 -Allyl-5 -O-(tert-butyldimethylsilyl)-3 -deoxythymidine?
The molecular formula of 3 -Allyl-5 -O-(tert-butyldimethylsilyl)-3 -deoxythymidine is C19H32N2O4Si.
What is the molecular weight of 3 -Allyl-5 -O-(tert-butyldimethylsilyl)-3 -deoxythymidine?
The molecular weight of 3 -Allyl-5 -O-(tert-butyldimethylsilyl)-3 -deoxythymidine is 380.21 g/mol.
Where can I buy 3 -Allyl-5 -O-(tert-butyldimethylsilyl)-3 -deoxythymidine?
You can request a quote for 3 -Allyl-5 -O-(tert-butyldimethylsilyl)-3 -deoxythymidine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 3 -Allyl-5 -O-(tert-butyldimethylsilyl)-3 -deoxythymidine?
Yes, KEHONG BIO provides custom synthesis services for 3 -Allyl-5 -O-(tert-butyldimethylsilyl)-3 -deoxythymidine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.