替尼达普 structure

替尼达普

TL;DR: 替尼达普 (CAS 120210-48-2) is a chemical compound with molecular formula C14H9ClN2O3S and molecular weight 320.00 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

替尼达普

5-chloro-2-hydroxy-3-(thiophene-2-carbonyl)indole-1-carboxamide

Also Known As: TENIDAP, Tenidapum, TENIDAP SODIUM, Tenidap sodium salt, Tenidapum [INN-Latin]

CAS: 120210-48-2
Molecular Formula C14H9ClN2O3S
Molecular Weight 320.00 g/mol
LogP 3.8
Topological Polar Surface Area 114.0 Ų
Hydrogen Bond Donors 2
Hydrogen Bond Acceptors 4
Rotatable Bonds 2
Exact Mass 320.00223
Heavy Atoms 21
Complexity 450.0

Chemical Identifiers

CAS Number 120210-48-2
SMILES C1=CSC(=C1)C(=O)C2=C(N(C3=C2C=C(C=C3)Cl)C(=O)N)O
InChIKey IZSFDUMVCVVWKW-UHFFFAOYSA-N

Patent-Derived Application Labels

Derived from 2 IPC patent classification(s) across the SureChEMBL global patent database.

Heterocyclic Building Blocks (13 patents) Pharmaceutical Intermediates (6 patents)

Product Overview

替尼达普 (CAS 120210-48-2), with molecular formula C14H9ClN2O3S and molecular weight 320.00 g/mol. IUPAC: 5-chloro-2-hydroxy-3-(thiophene-2-carbonyl)indole-1-carboxamide.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of 替尼达普

XLogP
3.8
TPSA (Topological Polar Surface Area)
114.0
Hydrogen Bond Donors
2
Hydrogen Bond Acceptors
4
Rotatable Bonds
2
Heavy Atoms
21
Complexity
450.0
Exact Mass
320.00223
Monoisotopic Mass
320.00223
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of 替尼达普

The XLogP value of 3.8 indicates that 替尼达普 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 114.0 Ų falls within the moderate polarity range, balancing permeability and solubility for 替尼达普. Following Lipinski's Rule of Five, 替尼达普 has 2 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of 替尼达普?

The CAS number of 替尼达普 is 120210-48-2.

What is the molecular formula of 替尼达普?

The molecular formula of 替尼达普 is C14H9ClN2O3S.

What is the molecular weight of 替尼达普?

The molecular weight of 替尼达普 is 320.00 g/mol.

Where can I buy 替尼达普?

You can request a quote for 替尼达普 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for 替尼达普?

Yes, KEHONG BIO provides custom synthesis services for 替尼达普 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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