2-desamino-2,3-dimethyl-N(10)-propargyl-5,8-dideazafolic acid structure

2-desamino-2,3-dimethyl-N(10)-propargyl-5,8-dideazafolic acid

TL;DR: 2-desamino-2,3-dimethyl-N(10)-propargyl-5,8-dideazafolic acid (CAS 119820-56-3) is a chemical compound with molecular formula C26H26N4O6 and molecular weight 490.19 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

(2S)-2-[[4-[(2,3-dimethyl-4-oxoquinazolin-6-yl)methyl-prop-2-ynylamino]benzoyl]amino]pentanedioic acid

Also Known As: 2-Deamino-2,3-DM-pddf, 2-Desamino-2,3-dimethyl-N(10)-propargyl-5,8-dideazafolic acid, (2S)-2-[[4-[(2,3-dimethyl-4-oxoquinazolin-6-yl)methyl-prop-2-ynylamino]benzoyl]amino]pentanedioic acid, 2-desamino-2,3-dimethyl-N10-propargyl-5,8-dideazafolate, L-Glutamic acid, N-(4-(((3,4-dihydro-2,3-dimethyl-4-oxo-6-quinazolinyl)methyl)-2-propynylamino)benzoyl)-

CAS: 119820-56-3
Molecular Formula C26H26N4O6
Molecular Weight 490.19 g/mol
LogP 1.4
Topological Polar Surface Area 140.0 Ų
Hydrogen Bond Donors 3
Hydrogen Bond Acceptors 8
Rotatable Bonds 10
Exact Mass 490.18524
Heavy Atoms 36
Complexity 932.0

Chemical Identifiers

CAS Number 119820-56-3
SMILES CC1=NC2=C(C=C(C=C2)CN(CC#C)C3=CC=C(C=C3)C(=O)N[C@@H](CCC(=O)O)C(=O)O)C(=O)N1C
InChIKey ZZLZQCHJVCQSAK-QFIPXVFZSA-N

Product Overview

2-desamino-2,3-dimethyl-N(10)-propargyl-5,8-dideazafolic acid (CAS 119820-56-3), with molecular formula C26H26N4O6 and molecular weight 490.19 g/mol. IUPAC: (2S)-2-[[4-[(2,3-dimethyl-4-oxoquinazolin-6-yl)methyl-prop-2-ynylamino]benzoyl]amino]pentanedioic acid.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
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Chemical Property Profile of 2-desamino-2,3-dimethyl-N(10)-propargyl-5,8-dideazafolic acid

XLogP
1.4
TPSA (Topological Polar Surface Area)
140.0
Hydrogen Bond Donors
3
Hydrogen Bond Acceptors
8
Rotatable Bonds
10
Heavy Atoms
36
Complexity
932.0
Exact Mass
490.18524
Monoisotopic Mass
490.18524
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of 2-desamino-2,3-dimethyl-N(10)-propargyl-5,8-dideazafolic acid

The XLogP value of 1.4 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 2-desamino-2,3-dimethyl-N(10)-propargyl-5,8-dideazafolic acid. The TPSA of 140.0 Ų indicates high polarity, suggesting 2-desamino-2,3-dimethyl-N(10)-propargyl-5,8-dideazafolic acid may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, 2-desamino-2,3-dimethyl-N(10)-propargyl-5,8-dideazafolic acid has 3 hydrogen bond donor(s) and 8 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of 2-desamino-2,3-dimethyl-N(10)-propargyl-5,8-dideazafolic acid?

The CAS number of 2-desamino-2,3-dimethyl-N(10)-propargyl-5,8-dideazafolic acid is 119820-56-3.

What is the molecular formula of 2-desamino-2,3-dimethyl-N(10)-propargyl-5,8-dideazafolic acid?

The molecular formula of 2-desamino-2,3-dimethyl-N(10)-propargyl-5,8-dideazafolic acid is C26H26N4O6.

What is the molecular weight of 2-desamino-2,3-dimethyl-N(10)-propargyl-5,8-dideazafolic acid?

The molecular weight of 2-desamino-2,3-dimethyl-N(10)-propargyl-5,8-dideazafolic acid is 490.19 g/mol.

Where can I buy 2-desamino-2,3-dimethyl-N(10)-propargyl-5,8-dideazafolic acid?

You can request a quote for 2-desamino-2,3-dimethyl-N(10)-propargyl-5,8-dideazafolic acid directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for 2-desamino-2,3-dimethyl-N(10)-propargyl-5,8-dideazafolic acid?

Yes, KEHONG BIO provides custom synthesis services for 2-desamino-2,3-dimethyl-N(10)-propargyl-5,8-dideazafolic acid and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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