10-Methyl-20(RS)-Camptothecin
TL;DR: 10-Methyl-20(RS)-Camptothecin (CAS 119464-29-8) is a chemical compound with molecular formula C21H18N2O4 and molecular weight 362.13 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
19-ethyl-19-hydroxy-7-methyl-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2(11),3,5,7,9,15(20)-heptaene-14,18-dione
Also Known As: 10-Methyl-20(RS)-Camptothecin, 10-methyl-(20RS)-camptothecin, 10-Methyl-20-(RS)-Camptothecin, 1H-Pyrano(3',4':6,7)indolizino(1,2-b)quinoline-3,14(4H,12H)-dione, 4-ethyl-4-hydroxy-9-methyl-, 1H-Pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione,4-ethyl-4-hydroxy-9-methyl-
| Molecular Formula | C21H18N2O4 |
|---|---|
| Molecular Weight | 362.13 g/mol |
| LogP | 1.4 |
| Topological Polar Surface Area | 79.7 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 1 |
| Exact Mass | 362.12665 |
| Heavy Atoms | 27 |
| Complexity | 772.0 |
Chemical Identifiers
| CAS Number | 119464-29-8 |
|---|---|
| SMILES | CCC1(C2=C(COC1=O)C(=O)N3CC4=C(C3=C2)N=C5C=CC(=CC5=C4)C)O |
| InChIKey | FREMMFBXXMQTKV-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 1 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
10-Methyl-20(RS)-Camptothecin (CAS 119464-29-8), with molecular formula C21H18N2O4 and molecular weight 362.13 g/mol. IUPAC: 19-ethyl-19-hydroxy-7-methyl-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2(11),3,5,7,9,15(20)-heptaene-14,18-dione.
Chemical Property Profile of 10-Methyl-20(RS)-Camptothecin
Property Insights of 10-Methyl-20(RS)-Camptothecin
The XLogP value of 1.4 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 10-Methyl-20(RS)-Camptothecin. The TPSA of 79.7 Ų falls within the moderate polarity range, balancing permeability and solubility for 10-Methyl-20(RS)-Camptothecin. Following Lipinski's Rule of Five, 10-Methyl-20(RS)-Camptothecin has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 10-Methyl-20(RS)-Camptothecin?
The CAS number of 10-Methyl-20(RS)-Camptothecin is 119464-29-8.
What is the molecular formula of 10-Methyl-20(RS)-Camptothecin?
The molecular formula of 10-Methyl-20(RS)-Camptothecin is C21H18N2O4.
What is the molecular weight of 10-Methyl-20(RS)-Camptothecin?
The molecular weight of 10-Methyl-20(RS)-Camptothecin is 362.13 g/mol.
Where can I buy 10-Methyl-20(RS)-Camptothecin?
You can request a quote for 10-Methyl-20(RS)-Camptothecin directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 10-Methyl-20(RS)-Camptothecin?
Yes, KEHONG BIO provides custom synthesis services for 10-Methyl-20(RS)-Camptothecin and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.