6-Chloro-4-(2-fluorophenyl)-2-methylquinazoline
TL;DR: 6-Chloro-4-(2-fluorophenyl)-2-methylquinazoline (CAS 119401-13-7) is a chemical compound with molecular formula C15H10ClFN2 and molecular weight 272.05 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
6-chloro-4-(2-fluorophenyl)-2-methylquinazoline
Also Known As: 6-chloro-4-(2-fluorophenyl)-2-methylquinazoline, Midazolam EP Impurity H, Midazolam BP Impurity H, 6-Chloro-2-methyl-4-(2-fluorophenyl)quinazoline, MIDAZOLAM IMPURITY H [EP IMPURITY]
| Molecular Formula | C15H10ClFN2 |
|---|---|
| Molecular Weight | 272.05 g/mol |
| LogP | 4.3 |
| Topological Polar Surface Area | 25.8 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 1 |
| Exact Mass | 272.05167 |
| Heavy Atoms | 19 |
| Complexity | 315.0 |
Chemical Identifiers
| CAS Number | 119401-13-7 |
|---|---|
| SMILES | CC1=NC2=C(C=C(C=C2)Cl)C(=N1)C3=CC=CC=C3F |
| InChIKey | XYJIBRYJJRDFOQ-UHFFFAOYSA-N |
Product Overview
6-Chloro-4-(2-fluorophenyl)-2-methylquinazoline (CAS 119401-13-7), with molecular formula C15H10ClFN2 and molecular weight 272.05 g/mol. IUPAC: 6-chloro-4-(2-fluorophenyl)-2-methylquinazoline.
Chemical Property Profile of 6-Chloro-4-(2-fluorophenyl)-2-methylquinazoline
Property Insights of 6-Chloro-4-(2-fluorophenyl)-2-methylquinazoline
The XLogP value of 4.3 indicates that 6-Chloro-4-(2-fluorophenyl)-2-methylquinazoline is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 25.8 Ų, 6-Chloro-4-(2-fluorophenyl)-2-methylquinazoline exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 6-Chloro-4-(2-fluorophenyl)-2-methylquinazoline has 0 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 6-Chloro-4-(2-fluorophenyl)-2-methylquinazoline?
The CAS number of 6-Chloro-4-(2-fluorophenyl)-2-methylquinazoline is 119401-13-7.
What is the molecular formula of 6-Chloro-4-(2-fluorophenyl)-2-methylquinazoline?
The molecular formula of 6-Chloro-4-(2-fluorophenyl)-2-methylquinazoline is C15H10ClFN2.
What is the molecular weight of 6-Chloro-4-(2-fluorophenyl)-2-methylquinazoline?
The molecular weight of 6-Chloro-4-(2-fluorophenyl)-2-methylquinazoline is 272.05 g/mol.
Where can I buy 6-Chloro-4-(2-fluorophenyl)-2-methylquinazoline?
You can request a quote for 6-Chloro-4-(2-fluorophenyl)-2-methylquinazoline directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 6-Chloro-4-(2-fluorophenyl)-2-methylquinazoline?
Yes, KEHONG BIO provides custom synthesis services for 6-Chloro-4-(2-fluorophenyl)-2-methylquinazoline and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.