Neomycin
TL;DR: Neomycin (CAS 119-04-0) is a chemical compound with molecular formula C23H46N6O13 and molecular weight 614.31 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(2R,3S,4R,5R,6R)-5-amino-2-(aminomethyl)-6-[(1R,2R,3S,4R,6S)-4,6-diamino-2-[(2S,3R,4S,5R)-4-[(2R,3R,4R,5S,6S)-3-amino-6-(aminomethyl)-4,5-dihydroxyoxan-2-yl]oxy-3-hydroxy-5-(hydroxymethyl)oxolan-2-yl]oxy-3-hydroxycyclohexyl]oxyoxane-3,4-diol
Also Known As: neomycin, Framycetin, NEOMYCIN B, Fradiomycin, Soframycin
| Molecular Formula | C23H46N6O13 |
|---|---|
| Molecular Weight | 614.31 g/mol |
| LogP | -9.0 |
| Topological Polar Surface Area | 353.0 Ų |
| Hydrogen Bond Donors | 13 |
| Hydrogen Bond Acceptors | 19 |
| Rotatable Bonds | 9 |
| Exact Mass | 614.31226 |
| Heavy Atoms | 42 |
| Complexity | 872.0 |
| Melting Point | 6 °C (sulfate form) |
| Solubility | Soluble in water ... solutions up to 250 mg/mL may be prepared |
| Refractive Index | 1.541 (ALPHA), ISOTROPIC /NEOMICIN SULFATE/ |
Chemical Identifiers
| CAS Number | 119-04-0 |
|---|---|
| SMILES | C1[C@H]([C@@H]([C@H]([C@@H]([C@H]1N)O[C@@H]2[C@@H]([C@H]([C@@H]([C@H](O2)CN)O)O)N)O[C@H]3[C@@H]([C@@H]([C@H](O3)CO)O[C@@H]4[C@@H]([C@H]([C@@H]([C@@H](O4)CN)O)O)N)O)O)N |
| InChIKey | PGBHMTALBVVCIT-VCIWKGPPSA-N |
Patent-Derived Application Labels
Derived from 21 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
Neomycin (CAS 119-04-0), with molecular formula C23H46N6O13 and molecular weight 614.31 g/mol. IUPAC: (2R,3S,4R,5R,6R)-5-amino-2-(aminomethyl)-6-[(1R,2R,3S,4R,6S)-4,6-diamino-2-[(2S,3R,4S,5R)-4-[(2R,3R,4R,5S,6S)-3-amino-6-(aminomethyl)-4,5-dihydroxyoxan-2-yl]oxy-3-hydroxy-5-(hydroxymethyl)oxolan-2-yl]oxy-3-hydroxycyclohexyl]oxyoxane-3,4-diol.
Chemical Property Profile of Neomycin
Property Insights of Neomycin
The XLogP value of -9.0 indicates that Neomycin is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 353.0 Ų indicates high polarity, suggesting Neomycin may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Neomycin has 13 hydrogen bond donor(s) and 19 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Neomycin?
The CAS number of Neomycin is 119-04-0.
What is the molecular formula of Neomycin?
The molecular formula of Neomycin is C23H46N6O13.
What is the molecular weight of Neomycin?
The molecular weight of Neomycin is 614.31 g/mol.
Where can I buy Neomycin?
You can request a quote for Neomycin directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Neomycin?
Yes, KEHONG BIO provides custom synthesis services for Neomycin and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.