Dabelotine structure

Dabelotine

TL;DR: Dabelotine (CAS 118976-38-8) is a chemical compound with molecular formula C15H22N2O2 and molecular weight 262.17 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

2-[(1-methyl-3,4-dihydro-2H-quinolin-8-yl)oxymethyl]morpholine

Also Known As: Dabelotine, dabelotina, Dabelotine [INN], dabelotinum, Z-Ser-OH

CAS: 118976-38-8
Molecular Formula C15H22N2O2
Molecular Weight 262.17 g/mol
LogP 1.7
Topological Polar Surface Area 33.7 Ų
Hydrogen Bond Donors 1
Hydrogen Bond Acceptors 4
Rotatable Bonds 3
Exact Mass 262.16812
Heavy Atoms 19
Complexity 287.0

Chemical Identifiers

CAS Number 118976-38-8
SMILES CN1CCCC2=C1C(=CC=C2)OCC3CNCCO3
InChIKey VXQWMLATWQSCBE-UHFFFAOYSA-N

Patent-Derived Application Labels

Derived from 2 IPC patent classification(s) across the SureChEMBL global patent database.

Heterocyclic Building Blocks (3 patents) Pharmaceutical Intermediates (1 patents)

Product Overview

Dabelotine (CAS 118976-38-8), with molecular formula C15H22N2O2 and molecular weight 262.17 g/mol. IUPAC: 2-[(1-methyl-3,4-dihydro-2H-quinolin-8-yl)oxymethyl]morpholine.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Dabelotine

XLogP
1.7
TPSA (Topological Polar Surface Area)
33.7
Hydrogen Bond Donors
1
Hydrogen Bond Acceptors
4
Rotatable Bonds
3
Heavy Atoms
19
Complexity
287.0
Exact Mass
262.16812
Monoisotopic Mass
262.16812
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Dabelotine

The XLogP value of 1.7 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Dabelotine. With a topological polar surface area (TPSA) of 33.7 Ų, Dabelotine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Dabelotine has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Dabelotine?

The CAS number of Dabelotine is 118976-38-8.

What is the molecular formula of Dabelotine?

The molecular formula of Dabelotine is C15H22N2O2.

What is the molecular weight of Dabelotine?

The molecular weight of Dabelotine is 262.17 g/mol.

Where can I buy Dabelotine?

You can request a quote for Dabelotine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Dabelotine?

Yes, KEHONG BIO provides custom synthesis services for Dabelotine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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