Tromethamine hydrochloride
TL;DR: Tromethamine hydrochloride (CAS 1185-53-1) is a chemical compound with molecular formula C4H12ClNO3 and molecular weight 157.05 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-amino-2-(hydroxymethyl)propane-1,3-diol;hydrochloride
Also Known As: Tris hydrochloride, TRIS HCl, Tromethamine hydrochloride, Tris-HCl, Tromethamine HCl
| Molecular Formula | C4H12ClNO3 |
|---|---|
| Molecular Weight | 157.05 g/mol |
| LogP | -1.92 |
| Topological Polar Surface Area | 86.7 Ų |
| Hydrogen Bond Donors | 5 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 3 |
| Exact Mass | 157.05057 |
| Heavy Atoms | 9 |
| Complexity | 54.0 |
Chemical Identifiers
| CAS Number | 1185-53-1 |
|---|---|
| SMILES | C(C(CO)(CO)N)O.Cl |
| InChIKey | QKNYBSVHEMOAJP-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 21 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
Tromethamine hydrochloride (CAS 1185-53-1), with molecular formula C4H12ClNO3 and molecular weight 157.05 g/mol. IUPAC: 2-amino-2-(hydroxymethyl)propane-1,3-diol;hydrochloride.
Chemical Property Profile of Tromethamine hydrochloride
Property Insights of Tromethamine hydrochloride
The XLogP value of -1.92 indicates that Tromethamine hydrochloride is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 86.7 Ų falls within the moderate polarity range, balancing permeability and solubility for Tromethamine hydrochloride. Following Lipinski's Rule of Five, Tromethamine hydrochloride has 5 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Tromethamine hydrochloride?
The CAS number of Tromethamine hydrochloride is 1185-53-1.
What is the molecular formula of Tromethamine hydrochloride?
The molecular formula of Tromethamine hydrochloride is C4H12ClNO3.
What is the molecular weight of Tromethamine hydrochloride?
The molecular weight of Tromethamine hydrochloride is 157.05 g/mol.
Where can I buy Tromethamine hydrochloride?
You can request a quote for Tromethamine hydrochloride directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Tromethamine hydrochloride?
Yes, KEHONG BIO provides custom synthesis services for Tromethamine hydrochloride and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.