RefChem:284322
TL;DR: RefChem:284322 (CAS 118449-24-4) is a chemical compound with molecular formula C18H17ClFN3OS and molecular weight 377.08 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
7-chloro-2-[2-(dimethylamino)ethylsulfanyl]-3-(3-fluorophenyl)quinazolin-4-one
Also Known As: 4(3H)-Quinazolinone, 7-chloro-2-((2-(dimethylamino)ethyl)thio)-3-(3-fluorophenyl)-, 7-Chloro-2-((2-(dimethylamino)ethyl)thio)-3-(3-fluorophenyl)-4(3H)-quinazolinone, 7-chloro-2-{[2-(dimethylamino)ethyl]sulfanyl}-3-(3-fluorophenyl)quinazolin-4(3h)-one, 7-chloro-2-(2-dimethylaminoethylsulfanyl)-3-(3-fluorophenyl)quinazolin-4-one, RefChem:284322
| Molecular Formula | C18H17ClFN3OS |
|---|---|
| Molecular Weight | 377.08 g/mol |
| LogP | 4.1 |
| Topological Polar Surface Area | 61.2 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 5 |
| Exact Mass | 377.07648 |
| Heavy Atoms | 25 |
| Complexity | 519.0 |
Chemical Identifiers
| CAS Number | 118449-24-4 |
|---|---|
| SMILES | CN(C)CCSC1=NC2=C(C=CC(=C2)Cl)C(=O)N1C3=CC(=CC=C3)F |
| InChIKey | DWCNHGOLXASIGJ-UHFFFAOYSA-N |
Product Overview
RefChem:284322 (CAS 118449-24-4), with molecular formula C18H17ClFN3OS and molecular weight 377.08 g/mol. IUPAC: 7-chloro-2-[2-(dimethylamino)ethylsulfanyl]-3-(3-fluorophenyl)quinazolin-4-one.
Chemical Property Profile of RefChem:284322
Property Insights of RefChem:284322
The XLogP value of 4.1 indicates that RefChem:284322 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 61.2 Ų falls within the moderate polarity range, balancing permeability and solubility for RefChem:284322. Following Lipinski's Rule of Five, RefChem:284322 has 0 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of RefChem:284322?
The CAS number of RefChem:284322 is 118449-24-4.
What is the molecular formula of RefChem:284322?
The molecular formula of RefChem:284322 is C18H17ClFN3OS.
What is the molecular weight of RefChem:284322?
The molecular weight of RefChem:284322 is 377.08 g/mol.
Where can I buy RefChem:284322?
You can request a quote for RefChem:284322 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for RefChem:284322?
Yes, KEHONG BIO provides custom synthesis services for RefChem:284322 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.