AF-DX-384
TL;DR: AF-DX-384 (CAS 118290-26-9) is a chemical compound with molecular formula C27H38N6O2 and molecular weight 478.31 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-[2-[2-[(dipropylamino)methyl]piperidin-1-yl]ethyl]-6-oxo-5H-pyrido[2,3-b][1,4]benzodiazepine-11-carboxamide
Also Known As: Afdx 384, af-dx384, AF-DX 384 Free Base, AF-DX 384 methanesulfonate, [3H]AF DX-384
| Molecular Formula | C27H38N6O2 |
|---|---|
| Molecular Weight | 478.31 g/mol |
| LogP | 2.8 |
| Topological Polar Surface Area | 80.8 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 9 |
| Exact Mass | 478.30563 |
| Heavy Atoms | 35 |
| Complexity | 685.0 |
Chemical Identifiers
| CAS Number | 118290-26-9 |
|---|---|
| SMILES | CCCN(CCC)CC1CCCCN1CCNC(=O)N2C3=CC=CC=C3C(=O)NC4=C2N=CC=C4 |
| InChIKey | MZDYABXXPZNUCT-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 2 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
AF-DX-384 (CAS 118290-26-9), with molecular formula C27H38N6O2 and molecular weight 478.31 g/mol. IUPAC: N-[2-[2-[(dipropylamino)methyl]piperidin-1-yl]ethyl]-6-oxo-5H-pyrido[2,3-b][1,4]benzodiazepine-11-carboxamide.
Chemical Property Profile of AF-DX-384
Property Insights of AF-DX-384
The XLogP value of 2.8 suggests moderate lipophilicity, balancing water solubility and membrane permeability for AF-DX-384. The TPSA of 80.8 Ų falls within the moderate polarity range, balancing permeability and solubility for AF-DX-384. Following Lipinski's Rule of Five, AF-DX-384 has 2 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of AF-DX-384?
The CAS number of AF-DX-384 is 118290-26-9.
What is the molecular formula of AF-DX-384?
The molecular formula of AF-DX-384 is C27H38N6O2.
What is the molecular weight of AF-DX-384?
The molecular weight of AF-DX-384 is 478.31 g/mol.
Where can I buy AF-DX-384?
You can request a quote for AF-DX-384 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for AF-DX-384?
Yes, KEHONG BIO provides custom synthesis services for AF-DX-384 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.