2'-Hydroxy-2,4',6'-Trimethoxychalcone
TL;DR: 2'-Hydroxy-2,4',6'-Trimethoxychalcone (CAS 118267-80-4) is a chemical compound with molecular formula C18H18O5 and molecular weight 314.12 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(E)-1-(2-hydroxy-4,6-dimethoxyphenyl)-3-(2-methoxyphenyl)prop-2-en-1-one
Also Known As: 2'-Hydroxy-2,4',6'-trimethoxychalcone, 2-HYDROXY-2',4',6'-TRIMETHOXYCHALCONE, J1.918.348C, 2'-HYDROXY-2,4,6'-TRIMETHOXYCHALCONE, (E)-1-(2-hydroxy-4,6-dimethoxyphenyl)-3-(2-methoxyphenyl)prop-2-en-1-one
| Molecular Formula | C18H18O5 |
|---|---|
| Molecular Weight | 314.12 g/mol |
| LogP | 3.8 |
| Topological Polar Surface Area | 65.0 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 6 |
| Exact Mass | 314.11542 |
| Heavy Atoms | 23 |
| Complexity | 408.0 |
Chemical Identifiers
| CAS Number | 118267-80-4 |
|---|---|
| SMILES | COC1=CC=CC=C1/C=C/C(=O)C2=C(C=C(C=C2OC)OC)O |
| InChIKey | KKTYCZKXENFEJP-CMDGGOBGSA-N |
Product Overview
2'-Hydroxy-2,4',6'-Trimethoxychalcone (CAS 118267-80-4), with molecular formula C18H18O5 and molecular weight 314.12 g/mol. IUPAC: (E)-1-(2-hydroxy-4,6-dimethoxyphenyl)-3-(2-methoxyphenyl)prop-2-en-1-one.
Chemical Property Profile of 2'-Hydroxy-2,4',6'-Trimethoxychalcone
Property Insights of 2'-Hydroxy-2,4',6'-Trimethoxychalcone
The XLogP value of 3.8 indicates that 2'-Hydroxy-2,4',6'-Trimethoxychalcone is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 65.0 Ų falls within the moderate polarity range, balancing permeability and solubility for 2'-Hydroxy-2,4',6'-Trimethoxychalcone. Following Lipinski's Rule of Five, 2'-Hydroxy-2,4',6'-Trimethoxychalcone has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 2'-Hydroxy-2,4',6'-Trimethoxychalcone?
The CAS number of 2'-Hydroxy-2,4',6'-Trimethoxychalcone is 118267-80-4.
What is the molecular formula of 2'-Hydroxy-2,4',6'-Trimethoxychalcone?
The molecular formula of 2'-Hydroxy-2,4',6'-Trimethoxychalcone is C18H18O5.
What is the molecular weight of 2'-Hydroxy-2,4',6'-Trimethoxychalcone?
The molecular weight of 2'-Hydroxy-2,4',6'-Trimethoxychalcone is 314.12 g/mol.
Where can I buy 2'-Hydroxy-2,4',6'-Trimethoxychalcone?
You can request a quote for 2'-Hydroxy-2,4',6'-Trimethoxychalcone directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 2'-Hydroxy-2,4',6'-Trimethoxychalcone?
Yes, KEHONG BIO provides custom synthesis services for 2'-Hydroxy-2,4',6'-Trimethoxychalcone and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.