AZT glucuronide
TL;DR: AZT glucuronide (CAS 117675-21-5) is a chemical compound with molecular formula C16H21N5O10 and molecular weight 443.13 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(2S,3S,4S,5R)-6-[[(2S)-3-azido-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy]-3,4,5-trihydroxyoxane-2-carboxylic acid
Also Known As: AZT glucuronide, Zidovudine glucuronide, GAZT, (2S,3S,4S,5R)-6-[[(2S)-3-azido-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy]-3,4,5-trihydroxyoxane-2-carboxylic acid, 3'-Azido-3'-deoxy-5'-O-beta-glucopyranuronosylthymidine
| Molecular Formula | C16H21N5O10 |
|---|---|
| Molecular Weight | 443.13 g/mol |
| LogP | -1.3 |
| Topological Polar Surface Area | 189.0 Ų |
| Hydrogen Bond Donors | 5 |
| Hydrogen Bond Acceptors | 12 |
| Rotatable Bonds | 6 |
| Exact Mass | 443.12885 |
| Heavy Atoms | 31 |
| Complexity | 830.0 |
Chemical Identifiers
| CAS Number | 117675-21-5 |
|---|---|
| SMILES | CC1=CN(C(=O)NC1=O)C2CC([C@H](O2)COC3[C@@H]([C@H]([C@@H]([C@H](O3)C(=O)O)O)O)O)N=[N+]=[N-] |
| InChIKey | NFXAJWJJNLWLOV-OTQDERTISA-N |
Product Overview
AZT glucuronide (CAS 117675-21-5), with molecular formula C16H21N5O10 and molecular weight 443.13 g/mol. IUPAC: (2S,3S,4S,5R)-6-[[(2S)-3-azido-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy]-3,4,5-trihydroxyoxane-2-carboxylic acid.
Chemical Property Profile of AZT glucuronide
Property Insights of AZT glucuronide
The XLogP value of -1.3 indicates that AZT glucuronide is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 189.0 Ų indicates high polarity, suggesting AZT glucuronide may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, AZT glucuronide has 5 hydrogen bond donor(s) and 12 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of AZT glucuronide?
The CAS number of AZT glucuronide is 117675-21-5.
What is the molecular formula of AZT glucuronide?
The molecular formula of AZT glucuronide is C16H21N5O10.
What is the molecular weight of AZT glucuronide?
The molecular weight of AZT glucuronide is 443.13 g/mol.
Where can I buy AZT glucuronide?
You can request a quote for AZT glucuronide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for AZT glucuronide?
Yes, KEHONG BIO provides custom synthesis services for AZT glucuronide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.