(S)-tert-butyl (2-(1H-indol-3-yl)-1-(5-(((6-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)methyl)thio)-1,3,4-oxadiazol-2-yl)ethyl)carbamate
概要：(S)-tert-butyl (2-(1H-indol-3-yl)-1-(5-(((6-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)methyl)thio)-1,3,4-oxadiazol-2-yl)ethyl)carbamate（CAS 1173674-22-0）是一种化学化合物，分子式为C23H26N6O5S，分子量为498.17 g/mol。河南科弘生物科技有限公司提供CRO/CDMO定制合成服务，支持克级到吨级规格。
tert-butyl N-[(1S)-2-(1H-indol-3-yl)-1-[5-[(6-methyl-2,4-dioxo-1H-pyrimidin-5-yl)methylsulfanyl]-1,3,4-oxadiazol-2-yl]ethyl]carbamate
又称：(S)-tert-butyl (2-(1H-indol-3-yl)-1-(5-(((6-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)methyl)thio)-1,3,4-oxadiazol-2-yl)ethyl)carbamate, tert-butyl [(1S)-1-(5-{[(2,4-dihydroxy-6-methylpyrimidin-5-yl)methyl]sulfanyl}-1,3,4-oxadiazol-2-yl)-2-(1H-indol-3-yl)ethyl]carbamate, tert-butyl N-[(1S)-2-(1H-indol-3-yl)-1-[5-[(6-methyl-2,4-dioxo-1H-pyrimidin-5-yl)methylsulfanyl]-1,3,4-oxadiazol-2-yl]ethyl]carbamate
| 分子式 | C23H26N6O5S |
|---|---|
| 分子量 | 498.17 g/mol |
| LogP | 3.33672 |
| 拓扑极性表面积 | 158.76 Ų |
| 氢键供体数 | 4 |
| 氢键受体数 | 8 |
| 可旋转键数 | 7 |
| 精确质量 | 498.16855 |
| 重原子数 | 35 |
| 复杂度 | 1461.3285 |
化学标识符
| CAS 编号 | 1173674-22-0 |
|---|---|
| SMILES | CC1=C(C(=O)NC(=O)N1)CSC2=NN=C(O2)[C@H](CC3=CNC4=CC=CC=C43)NC(=O)OC(C)(C)C |
产品概述
(S)-tert-butyl (2-(1H-indol-3-yl)-1-(5-(((6-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)methyl)thio)-1,3,4-oxadiazol-2-yl)ethyl)carbamate（CAS 1173674-22-0），分子式为C23H26N6O5S，分子量为498.17 g/mol。IUPAC名：tert-butyl N-[(1S)-2-(1H-indol-3-yl)-1-[5-[(6-methyl-2,4-dioxo-1H-pyrimidin-5-yl)methylsulfanyl]-1,3,4-oxadiazol-2-yl]ethyl]carbamate。
(S)-tert-butyl (2-(1H-indol-3-yl)-1-(5-(((6-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)methyl)thio)-1,3,4-oxadiazol-2-yl)ethyl)carbamate化学性质概览
属性洞察：(S)-tert-butyl (2-(1H-indol-3-yl)-1-(5-(((6-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)methyl)thio)-1,3,4-oxadiazol-2-yl)ethyl)carbamate
(S)-tert-butyl (2-(1H-indol-3-yl)-1-(5-(((6-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)methyl)thio)-1,3,4-oxadiazol-2-yl)ethyl)carbamate的XLogP值为3.33672，表明该化合物具有亲脂性（脂溶性好），可能影响其吸收、分布和配方策略。 TPSA为158.76 Ų，极性较高，提示该化合物膜透过性可能受限但水溶性较好。 根据Lipinski五规则，(S)-tert-butyl (2-(1H-indol-3-yl)-1-(5-(((6-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)methyl)thio)-1,3,4-oxadiazol-2-yl)ethyl)carbamate有4个氢键供体和8个氢键受体，均在类药范围内，提示具有较好的口服生物利用度潜力。
常见问题
常见问题
(S)-tert-butyl (2-(1H-indol-3-yl)-1-(5-(((6-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)methyl)thio)-1,3,4-oxadiazol-2-yl)ethyl)carbamate的CAS号是多少？
(S)-tert-butyl (2-(1H-indol-3-yl)-1-(5-(((6-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)methyl)thio)-1,3,4-oxadiazol-2-yl)ethyl)carbamate的CAS号为1173674-22-0。
(S)-tert-butyl (2-(1H-indol-3-yl)-1-(5-(((6-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)methyl)thio)-1,3,4-oxadiazol-2-yl)ethyl)carbamate的分子式是什么？
(S)-tert-butyl (2-(1H-indol-3-yl)-1-(5-(((6-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)methyl)thio)-1,3,4-oxadiazol-2-yl)ethyl)carbamate的分子式为C23H26N6O5S。
(S)-tert-butyl (2-(1H-indol-3-yl)-1-(5-(((6-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)methyl)thio)-1,3,4-oxadiazol-2-yl)ethyl)carbamate的分子量是多少？
(S)-tert-butyl (2-(1H-indol-3-yl)-1-(5-(((6-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)methyl)thio)-1,3,4-oxadiazol-2-yl)ethyl)carbamate的分子量为498.17 g/mol。
在哪里可以购买(S)-tert-butyl (2-(1H-indol-3-yl)-1-(5-(((6-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)methyl)thio)-1,3,4-oxadiazol-2-yl)ethyl)carbamate？
您可以直接向科弘生物询价(S)-tert-butyl (2-(1H-indol-3-yl)-1-(5-(((6-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)methyl)thio)-1,3,4-oxadiazol-2-yl)ethyl)carbamate。联系我们或发送邮件至info@kehongbio.com获取报价和库存信息。
科弘生物是否提供(S)-tert-butyl (2-(1H-indol-3-yl)-1-(5-(((6-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)methyl)thio)-1,3,4-oxadiazol-2-yl)ethyl)carbamate的定制合成服务？
是的，科弘生物提供(S)-tert-butyl (2-(1H-indol-3-yl)-1-(5-(((6-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)methyl)thio)-1,3,4-oxadiazol-2-yl)ethyl)carbamate及相关化合物的定制合成服务。请联系我们并告知您的具体需求，包括数量、纯度和交期。