Flurazepam Hydrochloride
TL;DR: Flurazepam Hydrochloride (CAS 1172-18-5) is a chemical compound with molecular formula C21H25Cl3FN3O and molecular weight 459.10 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
7-chloro-1-[2-(diethylamino)ethyl]-5-(2-fluorophenyl)-3H-1,4-benzodiazepin-2-one;dihydrochloride
Also Known As: Flurazepam hydrochloride, Flurazepam dihydrochloride, Dalmane, Benozil, Lunipax
| Molecular Formula | C21H25Cl3FN3O |
|---|---|
| Molecular Weight | 459.10 g/mol |
| LogP | 4.85 |
| Topological Polar Surface Area | 35.9 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 6 |
| Exact Mass | 459.10474 |
| Heavy Atoms | 29 |
| Complexity | 540.0 |
| Melting Point | 406 to 217.8 °C (decomposes) |
| Solubility | greater than or equal to 100 mg/mL at 66 °F (NTP, 1992) |
Chemical Identifiers
| CAS Number | 1172-18-5 |
|---|---|
| SMILES | CCN(CC)CCN1C(=O)CN=C(C2=C1C=CC(=C2)Cl)C3=CC=CC=C3F.Cl.Cl |
| InChIKey | ZIIJJOPLRSCQNX-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 13 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
Flurazepam Hydrochloride (CAS 1172-18-5), with molecular formula C21H25Cl3FN3O and molecular weight 459.10 g/mol. IUPAC: 7-chloro-1-[2-(diethylamino)ethyl]-5-(2-fluorophenyl)-3H-1,4-benzodiazepin-2-one;dihydrochloride.
Chemical Property Profile of Flurazepam Hydrochloride
Property Insights of Flurazepam Hydrochloride
The XLogP value of 4.85 indicates that Flurazepam Hydrochloride is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 35.9 Ų, Flurazepam Hydrochloride exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Flurazepam Hydrochloride has 2 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Flurazepam Hydrochloride?
The CAS number of Flurazepam Hydrochloride is 1172-18-5.
What is the molecular formula of Flurazepam Hydrochloride?
The molecular formula of Flurazepam Hydrochloride is C21H25Cl3FN3O.
What is the molecular weight of Flurazepam Hydrochloride?
The molecular weight of Flurazepam Hydrochloride is 459.10 g/mol.
Where can I buy Flurazepam Hydrochloride?
You can request a quote for Flurazepam Hydrochloride directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Flurazepam Hydrochloride?
Yes, KEHONG BIO provides custom synthesis services for Flurazepam Hydrochloride and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.