2,6-Difluorophenylacetyl chloride structure

2,6-Difluorophenylacetyl chloride

TL;DR: 2,6-Difluorophenylacetyl chloride (CAS 116622-96-9) is a chemical compound with molecular formula C8H5ClF2O and molecular weight 190.00 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

2-(2,6-difluorophenyl)acetyl chloride

Also Known As: 2,6-Difluorophenylacetyl chloride, 2-(2,6-difluorophenyl)acetyl chloride, (2,6-difluoro-phenyl)-acetyl chloride, 2,6-Difluorophenylacetylchloride, (2,6-Difluorophenyl)acetyl chloride

CAS: 116622-96-9
Molecular Formula C8H5ClF2O
Molecular Weight 190.00 g/mol
LogP 2.2727
Topological Polar Surface Area 17.07 Ų
Hydrogen Bond Donors 0
Hydrogen Bond Acceptors 1
Rotatable Bonds 2
Exact Mass 189.9997
Heavy Atoms 12
Complexity 291.6762

Chemical Identifiers

CAS Number 116622-96-9
SMILES C1=CC(=C(C(=C1)F)CC(=O)Cl)F

Product Overview

2,6-Difluorophenylacetyl chloride (CAS 116622-96-9), with molecular formula C8H5ClF2O and molecular weight 190.00 g/mol. IUPAC: 2-(2,6-difluorophenyl)acetyl chloride.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of 2,6-Difluorophenylacetyl chloride

XLogP
2.2727
TPSA (Topological Polar Surface Area)
17.07
Hydrogen Bond Donors
0
Hydrogen Bond Acceptors
1
Rotatable Bonds
2
Heavy Atoms
12
Complexity
291.6762
Exact Mass
189.9997
Monoisotopic Mass
189.9997
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of 2,6-Difluorophenylacetyl chloride

The XLogP value of 2.2727 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 2,6-Difluorophenylacetyl chloride. With a topological polar surface area (TPSA) of 17.07 Ų, 2,6-Difluorophenylacetyl chloride exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 2,6-Difluorophenylacetyl chloride has 0 hydrogen bond donor(s) and 1 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of 2,6-Difluorophenylacetyl chloride?

The CAS number of 2,6-Difluorophenylacetyl chloride is 116622-96-9.

What is the molecular formula of 2,6-Difluorophenylacetyl chloride?

The molecular formula of 2,6-Difluorophenylacetyl chloride is C8H5ClF2O.

What is the molecular weight of 2,6-Difluorophenylacetyl chloride?

The molecular weight of 2,6-Difluorophenylacetyl chloride is 190.00 g/mol.

Where can I buy 2,6-Difluorophenylacetyl chloride?

You can request a quote for 2,6-Difluorophenylacetyl chloride directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for 2,6-Difluorophenylacetyl chloride?

Yes, KEHONG BIO provides custom synthesis services for 2,6-Difluorophenylacetyl chloride and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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