![1-Phenyl-4-[3-(2-thienyl)acryloyl]piperazine structure](/static/products/1165/116557-96-1.webp)
1-Phenyl-4-[3-(2-thienyl)acryloyl]piperazine
TL;DR: 1-Phenyl-4-[3-(2-thienyl)acryloyl]piperazine (CAS 116557-96-1) is a chemical compound with molecular formula C17H18N2OS and molecular weight 298.11 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(E)-1-(4-phenylpiperazin-1-yl)-3-thiophen-2-ylprop-2-en-1-one
Also Known As: 1-phenyl-4-[3-(2-thienyl)acryloyl]piperazine, BIM-0038179.P001, (2E)-1-(4-phenylpiperazin-1-yl)-3-(thiophen-2-yl)prop-2-en-1-one, (E)-1-(4-phenylpiperazin-1-yl)-3-thiophen-2-ylprop-2-en-1-one, (E)-1-(4-phenylpiperazin-1-yl)-3-(thiophen-2-yl)prop-2-en-1-one
| Molecular Formula | C17H18N2OS |
|---|---|
| Molecular Weight | 298.11 g/mol |
| LogP | 3.1101 |
| Topological Polar Surface Area | 23.55 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 3 |
| Exact Mass | 298.11398 |
| Heavy Atoms | 21 |
| Complexity | 598.98505 |
Chemical Identifiers
| CAS Number | 116557-96-1 |
|---|---|
| SMILES | C1CN(CCN1C2=CC=CC=C2)C(=O)/C=C/C3=CC=CS3 |
Product Overview
1-Phenyl-4-[3-(2-thienyl)acryloyl]piperazine (CAS 116557-96-1), with molecular formula C17H18N2OS and molecular weight 298.11 g/mol. IUPAC: (E)-1-(4-phenylpiperazin-1-yl)-3-thiophen-2-ylprop-2-en-1-one.
Chemical Property Profile of 1-Phenyl-4-[3-(2-thienyl)acryloyl]piperazine
Property Insights of 1-Phenyl-4-[3-(2-thienyl)acryloyl]piperazine
The XLogP value of 3.1101 indicates that 1-Phenyl-4-[3-(2-thienyl)acryloyl]piperazine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 23.55 Ų, 1-Phenyl-4-[3-(2-thienyl)acryloyl]piperazine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 1-Phenyl-4-[3-(2-thienyl)acryloyl]piperazine has 0 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 1-Phenyl-4-[3-(2-thienyl)acryloyl]piperazine?
The CAS number of 1-Phenyl-4-[3-(2-thienyl)acryloyl]piperazine is 116557-96-1.
What is the molecular formula of 1-Phenyl-4-[3-(2-thienyl)acryloyl]piperazine?
The molecular formula of 1-Phenyl-4-[3-(2-thienyl)acryloyl]piperazine is C17H18N2OS.
What is the molecular weight of 1-Phenyl-4-[3-(2-thienyl)acryloyl]piperazine?
The molecular weight of 1-Phenyl-4-[3-(2-thienyl)acryloyl]piperazine is 298.11 g/mol.
Where can I buy 1-Phenyl-4-[3-(2-thienyl)acryloyl]piperazine?
You can request a quote for 1-Phenyl-4-[3-(2-thienyl)acryloyl]piperazine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 1-Phenyl-4-[3-(2-thienyl)acryloyl]piperazine?
Yes, KEHONG BIO provides custom synthesis services for 1-Phenyl-4-[3-(2-thienyl)acryloyl]piperazine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.