Andrographin
TL;DR: Andrographin (CAS 1165-40-8) is a chemical compound with molecular formula C18H16O6 and molecular weight 328.09 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
5-hydroxy-7,8-dimethoxy-2-(2-methoxyphenyl)chromen-4-one
Also Known As: Andrographin, FLAVONE, 5-hydroxy-7,8,2'-trimethoxyflavone, Skullcapflavone I 2'-methyl ether, 2'-O-Methylskullcapflavone I
| Molecular Formula | C18H16O6 |
|---|---|
| Molecular Weight | 328.09 g/mol |
| LogP | 3.1914 |
| Topological Polar Surface Area | 78.13 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 4 |
| Exact Mass | 328.0947 |
| Heavy Atoms | 24 |
| Complexity | 957.6156 |
Chemical Identifiers
| CAS Number | 1165-40-8 |
|---|---|
| SMILES | COC1=CC=CC=C1C2=CC(=O)C3=C(O2)C(=C(C=C3O)OC)OC |
Product Overview
Andrographin (CAS 1165-40-8), with molecular formula C18H16O6 and molecular weight 328.09 g/mol. IUPAC: 5-hydroxy-7,8-dimethoxy-2-(2-methoxyphenyl)chromen-4-one.
Chemical Property Profile of Andrographin
Property Insights of Andrographin
The XLogP value of 3.1914 indicates that Andrographin is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 78.13 Ų falls within the moderate polarity range, balancing permeability and solubility for Andrographin. Following Lipinski's Rule of Five, Andrographin has 1 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Andrographin?
The CAS number of Andrographin is 1165-40-8.
What is the molecular formula of Andrographin?
The molecular formula of Andrographin is C18H16O6.
What is the molecular weight of Andrographin?
The molecular weight of Andrographin is 328.09 g/mol.
Where can I buy Andrographin?
You can request a quote for Andrographin directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Andrographin?
Yes, KEHONG BIO provides custom synthesis services for Andrographin and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.