Colchicine, derivative of
TL;DR: Colchicine, derivative of (CAS 116475-04-8) is a chemical compound with molecular formula C27H37N3O5 and molecular weight 483.27 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-[(7S)-10-(6-aminohexylamino)-1,2,3-trimethoxy-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-7-yl]acetamide
Also Known As: Colchicine, derivative of, AH-214/21074007, (S)-N-(10-((6-aminohexyl)amino)-1,2,3-trimethoxy-9-oxo-5,6,7,9-tetrahydrobenzo[a]heptalen-7-yl)acetamide, N-[(7S)-10-(6-aminohexylamino)-1,2,3-trimethoxy-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-7-yl]acetamide, N-{(7S)-10-[(6-aminohexyl)amino]-1,2,3-trimethoxy-9-oxo-5,6,7,9-tetrahydrobenzo[a]heptalen-7-yl}acetamide
| Molecular Formula | C27H37N3O5 |
|---|---|
| Molecular Weight | 483.27 g/mol |
| LogP | 3.794 |
| Topological Polar Surface Area | 111.91 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 7 |
| Rotatable Bonds | 11 |
| Exact Mass | 483.27332 |
| Heavy Atoms | 35 |
| Complexity | 1102.9514 |
Chemical Identifiers
| CAS Number | 116475-04-8 |
|---|---|
| SMILES | CC(=O)N[C@H]1CCC2=CC(=C(C(=C2C3=CC=C(C(=O)C=C13)NCCCCCCN)OC)OC)OC |
Product Overview
Colchicine, derivative of (CAS 116475-04-8), with molecular formula C27H37N3O5 and molecular weight 483.27 g/mol. IUPAC: N-[(7S)-10-(6-aminohexylamino)-1,2,3-trimethoxy-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-7-yl]acetamide.
Chemical Property Profile of Colchicine, derivative of
Property Insights of Colchicine, derivative of
The XLogP value of 3.794 indicates that Colchicine, derivative of is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 111.91 Ų falls within the moderate polarity range, balancing permeability and solubility for Colchicine, derivative of. Following Lipinski's Rule of Five, Colchicine, derivative of has 3 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Colchicine, derivative of?
The CAS number of Colchicine, derivative of is 116475-04-8.
What is the molecular formula of Colchicine, derivative of?
The molecular formula of Colchicine, derivative of is C27H37N3O5.
What is the molecular weight of Colchicine, derivative of?
The molecular weight of Colchicine, derivative of is 483.27 g/mol.
Where can I buy Colchicine, derivative of?
You can request a quote for Colchicine, derivative of directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Colchicine, derivative of?
Yes, KEHONG BIO provides custom synthesis services for Colchicine, derivative of and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.