PMET structure

PMET

TL;DR: PMET (CAS 116455-17-5) is a chemical compound with molecular formula C8H13N2O6P and molecular weight 264.05 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

2-(5-methyl-2,4-dioxopyrimidin-1-yl)ethoxymethylphosphonic acid

Also Known As: PMET, 2-Phosphonylmethoxyethyl-thymine, 1-[2-(phosphonomethoxy)ethyl]thymine, 2-purin-9-ylethoxymethylphosphonic acid, Phosphonic acid, ((2-(3,4-dihydro-5-methyl-2,4-dioxo-1(2H)-pyrimidinyl)ethoxy)methyl)-

CAS: 116455-17-5
Molecular Formula C8H13N2O6P
Molecular Weight 264.05 g/mol
LogP -2.4
Topological Polar Surface Area 116.0 Ų
Hydrogen Bond Donors 3
Hydrogen Bond Acceptors 6
Rotatable Bonds 5
Exact Mass 264.05112
Heavy Atoms 17
Complexity 401.0

Chemical Identifiers

CAS Number 116455-17-5
SMILES CC1=CN(C(=O)NC1=O)CCOCP(=O)(O)O
InChIKey RCQMOSJJIVCPJO-UHFFFAOYSA-N

Patent-Derived Application Labels

Derived from 3 IPC patent classification(s) across the SureChEMBL global patent database.

Heterocyclic Building Blocks (1 patents) Organometallic Reagents (3 patents) Pharmaceutical Intermediates (3 patents)

Product Overview

PMET (CAS 116455-17-5), with molecular formula C8H13N2O6P and molecular weight 264.05 g/mol. IUPAC: 2-(5-methyl-2,4-dioxopyrimidin-1-yl)ethoxymethylphosphonic acid.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of PMET

XLogP
-2.4
TPSA (Topological Polar Surface Area)
116.0
Hydrogen Bond Donors
3
Hydrogen Bond Acceptors
6
Rotatable Bonds
5
Heavy Atoms
17
Complexity
401.0
Exact Mass
264.05112
Monoisotopic Mass
264.05112
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of PMET

The XLogP value of -2.4 indicates that PMET is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 116.0 Ų falls within the moderate polarity range, balancing permeability and solubility for PMET. Following Lipinski's Rule of Five, PMET has 3 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of PMET?

The CAS number of PMET is 116455-17-5.

What is the molecular formula of PMET?

The molecular formula of PMET is C8H13N2O6P.

What is the molecular weight of PMET?

The molecular weight of PMET is 264.05 g/mol.

Where can I buy PMET?

You can request a quote for PMET directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for PMET?

Yes, KEHONG BIO provides custom synthesis services for PMET and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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