![(E)-2-Cyano-N-[5-(2,4-dichloro-benzyl)-thiazol-2-yl]-3-(1H-indol-3-yl)-acrylamide structure](/static/products/116/1164549-27-2.png)
(E)-2-Cyano-N-[5-(2,4-dichloro-benzyl)-thiazol-2-yl]-3-(1H-indol-3-yl)-acrylamide
TL;DR: (E)-2-Cyano-N-[5-(2,4-dichloro-benzyl)-thiazol-2-yl]-3-(1H-indol-3-yl)-acrylamide (CAS 1164549-27-2) is a chemical compound with molecular formula C22H14Cl2N4OS and molecular weight 452.03 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(E)-2-cyano-N-[5-[(2,4-dichlorophenyl)methyl]-1,3-thiazol-2-yl]-3-(1H-indol-3-yl)prop-2-enamide
Also Known As: (E)-2-Cyano-N-[5-(2,4-dichloro-benzyl)-thiazol-2-yl]-3-(1H-indol-3-yl)-acrylamide, (E)-2-cyano-N-[5-[(2,4-dichlorophenyl)methyl]-1,3-thiazol-2-yl]-3-(1H-indol-3-yl)prop-2-enamide, (E)-2-cyano-N-(5-(2,4-dichlorobenzyl)thiazol-2-yl)-3-(1H-indol-3-yl)acrylamide, (E)-2-cyano-N-[5-(2,4-dichlorobenzyl)thiazol-2-yl]-3-(1H-indol-3-yl)acrylamide, (2E)-2-cyano-N-[5-(2,4-dichlorobenzyl)-1,3-thiazol-2-yl]-3-(1H-indol-3-yl)prop-2-enamide
| Molecular Formula | C22H14Cl2N4OS |
|---|---|
| Molecular Weight | 452.03 g/mol |
| LogP | 6.06768 |
| Topological Polar Surface Area | 81.57 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 5 |
| Exact Mass | 452.02655 |
| Heavy Atoms | 30 |
| Complexity | 1316.1738 |
Chemical Identifiers
| CAS Number | 1164549-27-2 |
|---|---|
| SMILES | C1=CC=C2C(=C1)C(=CN2)/C=C(\C#N)/C(=O)NC3=NC=C(S3)CC4=C(C=C(C=C4)Cl)Cl |
Product Overview
(E)-2-Cyano-N-[5-(2,4-dichloro-benzyl)-thiazol-2-yl]-3-(1H-indol-3-yl)-acrylamide (CAS 1164549-27-2), with molecular formula C22H14Cl2N4OS and molecular weight 452.03 g/mol. IUPAC: (E)-2-cyano-N-[5-[(2,4-dichlorophenyl)methyl]-1,3-thiazol-2-yl]-3-(1H-indol-3-yl)prop-2-enamide.
Chemical Property Profile of (E)-2-Cyano-N-[5-(2,4-dichloro-benzyl)-thiazol-2-yl]-3-(1H-indol-3-yl)-acrylamide
Property Insights of (E)-2-Cyano-N-[5-(2,4-dichloro-benzyl)-thiazol-2-yl]-3-(1H-indol-3-yl)-acrylamide
The XLogP value of 6.06768 indicates that (E)-2-Cyano-N-[5-(2,4-dichloro-benzyl)-thiazol-2-yl]-3-(1H-indol-3-yl)-acrylamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 81.57 Ų falls within the moderate polarity range, balancing permeability and solubility for (E)-2-Cyano-N-[5-(2,4-dichloro-benzyl)-thiazol-2-yl]-3-(1H-indol-3-yl)-acrylamide. Following Lipinski's Rule of Five, (E)-2-Cyano-N-[5-(2,4-dichloro-benzyl)-thiazol-2-yl]-3-(1H-indol-3-yl)-acrylamide has 2 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (E)-2-Cyano-N-[5-(2,4-dichloro-benzyl)-thiazol-2-yl]-3-(1H-indol-3-yl)-acrylamide?
The CAS number of (E)-2-Cyano-N-[5-(2,4-dichloro-benzyl)-thiazol-2-yl]-3-(1H-indol-3-yl)-acrylamide is 1164549-27-2.
What is the molecular formula of (E)-2-Cyano-N-[5-(2,4-dichloro-benzyl)-thiazol-2-yl]-3-(1H-indol-3-yl)-acrylamide?
The molecular formula of (E)-2-Cyano-N-[5-(2,4-dichloro-benzyl)-thiazol-2-yl]-3-(1H-indol-3-yl)-acrylamide is C22H14Cl2N4OS.
What is the molecular weight of (E)-2-Cyano-N-[5-(2,4-dichloro-benzyl)-thiazol-2-yl]-3-(1H-indol-3-yl)-acrylamide?
The molecular weight of (E)-2-Cyano-N-[5-(2,4-dichloro-benzyl)-thiazol-2-yl]-3-(1H-indol-3-yl)-acrylamide is 452.03 g/mol.
Where can I buy (E)-2-Cyano-N-[5-(2,4-dichloro-benzyl)-thiazol-2-yl]-3-(1H-indol-3-yl)-acrylamide?
You can request a quote for (E)-2-Cyano-N-[5-(2,4-dichloro-benzyl)-thiazol-2-yl]-3-(1H-indol-3-yl)-acrylamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (E)-2-Cyano-N-[5-(2,4-dichloro-benzyl)-thiazol-2-yl]-3-(1H-indol-3-yl)-acrylamide?
Yes, KEHONG BIO provides custom synthesis services for (E)-2-Cyano-N-[5-(2,4-dichloro-benzyl)-thiazol-2-yl]-3-(1H-indol-3-yl)-acrylamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.