(E)-3-(furan-2-yl)-N-((2-morpholino-5-(trifluoromethyl)phenyl)carbamothioyl)acrylamide
TL;DR: (E)-3-(furan-2-yl)-N-((2-morpholino-5-(trifluoromethyl)phenyl)carbamothioyl)acrylamide (CAS 1164547-85-6) is a chemical compound with molecular formula C19H18F3N3O3S and molecular weight 425.10 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(E)-3-(furan-2-yl)-N-[[2-morpholin-4-yl-5-(trifluoromethyl)phenyl]carbamothioyl]prop-2-enamide
Also Known As: (E)-3-(furan-2-yl)-N-((2-morpholino-5-(trifluoromethyl)phenyl)carbamothioyl)acrylamide, (2E)-3-(furan-2-yl)-N-{[2-(morpholin-4-yl)-5-(trifluoromethyl)phenyl]carbamothioyl}prop-2-enamide, 1-((E)-3-Furan-2-yl-acryloyl)-3-(2-morpholin-4-yl-5-trifluoromethyl-phenyl)-thiourea, (E)-3-(furan-2-yl)-N-[[2-morpholin-4-yl-5-(trifluoromethyl)phenyl]carbamothioyl]prop-2-enamide
| Molecular Formula | C19H18F3N3O3S |
|---|---|
| Molecular Weight | 425.10 g/mol |
| LogP | 3.6614 |
| Topological Polar Surface Area | 66.74 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 4 |
| Exact Mass | 425.1021 |
| Heavy Atoms | 29 |
| Complexity | 891.8446 |
Chemical Identifiers
| CAS Number | 1164547-85-6 |
|---|---|
| SMILES | C1COCCN1C2=C(C=C(C=C2)C(F)(F)F)NC(=S)NC(=O)/C=C/C3=CC=CO3 |
Product Overview
(E)-3-(furan-2-yl)-N-((2-morpholino-5-(trifluoromethyl)phenyl)carbamothioyl)acrylamide (CAS 1164547-85-6), with molecular formula C19H18F3N3O3S and molecular weight 425.10 g/mol. IUPAC: (E)-3-(furan-2-yl)-N-[[2-morpholin-4-yl-5-(trifluoromethyl)phenyl]carbamothioyl]prop-2-enamide.
Chemical Property Profile of (E)-3-(furan-2-yl)-N-((2-morpholino-5-(trifluoromethyl)phenyl)carbamothioyl)acrylamide
Property Insights of (E)-3-(furan-2-yl)-N-((2-morpholino-5-(trifluoromethyl)phenyl)carbamothioyl)acrylamide
The XLogP value of 3.6614 indicates that (E)-3-(furan-2-yl)-N-((2-morpholino-5-(trifluoromethyl)phenyl)carbamothioyl)acrylamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 66.74 Ų falls within the moderate polarity range, balancing permeability and solubility for (E)-3-(furan-2-yl)-N-((2-morpholino-5-(trifluoromethyl)phenyl)carbamothioyl)acrylamide. Following Lipinski's Rule of Five, (E)-3-(furan-2-yl)-N-((2-morpholino-5-(trifluoromethyl)phenyl)carbamothioyl)acrylamide has 2 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (E)-3-(furan-2-yl)-N-((2-morpholino-5-(trifluoromethyl)phenyl)carbamothioyl)acrylamide?
The CAS number of (E)-3-(furan-2-yl)-N-((2-morpholino-5-(trifluoromethyl)phenyl)carbamothioyl)acrylamide is 1164547-85-6.
What is the molecular formula of (E)-3-(furan-2-yl)-N-((2-morpholino-5-(trifluoromethyl)phenyl)carbamothioyl)acrylamide?
The molecular formula of (E)-3-(furan-2-yl)-N-((2-morpholino-5-(trifluoromethyl)phenyl)carbamothioyl)acrylamide is C19H18F3N3O3S.
What is the molecular weight of (E)-3-(furan-2-yl)-N-((2-morpholino-5-(trifluoromethyl)phenyl)carbamothioyl)acrylamide?
The molecular weight of (E)-3-(furan-2-yl)-N-((2-morpholino-5-(trifluoromethyl)phenyl)carbamothioyl)acrylamide is 425.10 g/mol.
Where can I buy (E)-3-(furan-2-yl)-N-((2-morpholino-5-(trifluoromethyl)phenyl)carbamothioyl)acrylamide?
You can request a quote for (E)-3-(furan-2-yl)-N-((2-morpholino-5-(trifluoromethyl)phenyl)carbamothioyl)acrylamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (E)-3-(furan-2-yl)-N-((2-morpholino-5-(trifluoromethyl)phenyl)carbamothioyl)acrylamide?
Yes, KEHONG BIO provides custom synthesis services for (E)-3-(furan-2-yl)-N-((2-morpholino-5-(trifluoromethyl)phenyl)carbamothioyl)acrylamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.