N-(4,5-dihydro-1,3-thiazol-2-yl)-3-(4-methylphenyl)acrylamide
TL;DR: N-(4,5-dihydro-1,3-thiazol-2-yl)-3-(4-methylphenyl)acrylamide (CAS 1164535-42-5) is a chemical compound with molecular formula C13H14N2OS and molecular weight 246.08 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(E)-N-(4,5-dihydro-1,3-thiazol-2-yl)-3-(4-methylphenyl)prop-2-enamide
Also Known As: ML243 Analog, (E)-N-(4,5-dihydro-1,3-thiazol-2-yl)-3-(4-methylphenyl)prop-2-enamide, N-(4,5-dihydro-1,3-thiazol-2-yl)-3-(4-methylphenyl)acrylamide, (E)-3-(p-tolyl)-N-(2-thiazolin-2-yl)acrylamide, BRD-K71554540-001-04-4
| Molecular Formula | C13H14N2OS |
|---|---|
| Molecular Weight | 246.08 g/mol |
| LogP | 2.22722 |
| Topological Polar Surface Area | 41.46 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 2 |
| Exact Mass | 246.08269 |
| Heavy Atoms | 17 |
| Complexity | 462.81274 |
Chemical Identifiers
| CAS Number | 1164535-42-5 |
|---|---|
| SMILES | CC1=CC=C(C=C1)/C=C/C(=O)NC2=NCCS2 |
Product Overview
N-(4,5-dihydro-1,3-thiazol-2-yl)-3-(4-methylphenyl)acrylamide (CAS 1164535-42-5), with molecular formula C13H14N2OS and molecular weight 246.08 g/mol. IUPAC: (E)-N-(4,5-dihydro-1,3-thiazol-2-yl)-3-(4-methylphenyl)prop-2-enamide.
Chemical Property Profile of N-(4,5-dihydro-1,3-thiazol-2-yl)-3-(4-methylphenyl)acrylamide
Property Insights of N-(4,5-dihydro-1,3-thiazol-2-yl)-3-(4-methylphenyl)acrylamide
The XLogP value of 2.22722 suggests moderate lipophilicity, balancing water solubility and membrane permeability for N-(4,5-dihydro-1,3-thiazol-2-yl)-3-(4-methylphenyl)acrylamide. With a topological polar surface area (TPSA) of 41.46 Ų, N-(4,5-dihydro-1,3-thiazol-2-yl)-3-(4-methylphenyl)acrylamide exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, N-(4,5-dihydro-1,3-thiazol-2-yl)-3-(4-methylphenyl)acrylamide has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of N-(4,5-dihydro-1,3-thiazol-2-yl)-3-(4-methylphenyl)acrylamide?
The CAS number of N-(4,5-dihydro-1,3-thiazol-2-yl)-3-(4-methylphenyl)acrylamide is 1164535-42-5.
What is the molecular formula of N-(4,5-dihydro-1,3-thiazol-2-yl)-3-(4-methylphenyl)acrylamide?
The molecular formula of N-(4,5-dihydro-1,3-thiazol-2-yl)-3-(4-methylphenyl)acrylamide is C13H14N2OS.
What is the molecular weight of N-(4,5-dihydro-1,3-thiazol-2-yl)-3-(4-methylphenyl)acrylamide?
The molecular weight of N-(4,5-dihydro-1,3-thiazol-2-yl)-3-(4-methylphenyl)acrylamide is 246.08 g/mol.
Where can I buy N-(4,5-dihydro-1,3-thiazol-2-yl)-3-(4-methylphenyl)acrylamide?
You can request a quote for N-(4,5-dihydro-1,3-thiazol-2-yl)-3-(4-methylphenyl)acrylamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for N-(4,5-dihydro-1,3-thiazol-2-yl)-3-(4-methylphenyl)acrylamide?
Yes, KEHONG BIO provides custom synthesis services for N-(4,5-dihydro-1,3-thiazol-2-yl)-3-(4-methylphenyl)acrylamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.