(E)-N-(1H-benzimidazol-2-yl)-3-(4-fluorophenyl)prop-2-enamide
TL;DR: (E)-N-(1H-benzimidazol-2-yl)-3-(4-fluorophenyl)prop-2-enamide (CAS 1164535-07-2) is a chemical compound with molecular formula C16H12FN3O and molecular weight 281.10 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(E)-N-(1H-benzimidazol-2-yl)-3-(4-fluorophenyl)prop-2-enamide
Also Known As: N-1H-benzimidazol-2-yl-3-(4-fluorophenyl)acrylamide, (E)-N-(1H-benzimidazol-2-yl)-3-(4-fluorophenyl)prop-2-enamide, (2E)-N-benzimidazol-2-yl-3-(4-fluorophenyl)prop-2-enamide, (E)-N-(1H-benzimidazol-2-yl)-3-(4-fluorophenyl)acrylamide, (2E)-N-(1H-benzimidazol-2-yl)-3-(4-fluorophenyl)prop-2-enamide
| Molecular Formula | C16H12FN3O |
|---|---|
| Molecular Weight | 281.10 g/mol |
| LogP | 3.3539 |
| Topological Polar Surface Area | 57.78 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 3 |
| Exact Mass | 281.09644 |
| Heavy Atoms | 21 |
| Complexity | 772.75995 |
Chemical Identifiers
| CAS Number | 1164535-07-2 |
|---|---|
| SMILES | C1=CC=C2C(=C1)NC(=N2)NC(=O)/C=C/C3=CC=C(C=C3)F |
Product Overview
(E)-N-(1H-benzimidazol-2-yl)-3-(4-fluorophenyl)prop-2-enamide (CAS 1164535-07-2), with molecular formula C16H12FN3O and molecular weight 281.10 g/mol. IUPAC: (E)-N-(1H-benzimidazol-2-yl)-3-(4-fluorophenyl)prop-2-enamide.
Chemical Property Profile of (E)-N-(1H-benzimidazol-2-yl)-3-(4-fluorophenyl)prop-2-enamide
Property Insights of (E)-N-(1H-benzimidazol-2-yl)-3-(4-fluorophenyl)prop-2-enamide
The XLogP value of 3.3539 indicates that (E)-N-(1H-benzimidazol-2-yl)-3-(4-fluorophenyl)prop-2-enamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 57.78 Ų, (E)-N-(1H-benzimidazol-2-yl)-3-(4-fluorophenyl)prop-2-enamide exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, (E)-N-(1H-benzimidazol-2-yl)-3-(4-fluorophenyl)prop-2-enamide has 2 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (E)-N-(1H-benzimidazol-2-yl)-3-(4-fluorophenyl)prop-2-enamide?
The CAS number of (E)-N-(1H-benzimidazol-2-yl)-3-(4-fluorophenyl)prop-2-enamide is 1164535-07-2.
What is the molecular formula of (E)-N-(1H-benzimidazol-2-yl)-3-(4-fluorophenyl)prop-2-enamide?
The molecular formula of (E)-N-(1H-benzimidazol-2-yl)-3-(4-fluorophenyl)prop-2-enamide is C16H12FN3O.
What is the molecular weight of (E)-N-(1H-benzimidazol-2-yl)-3-(4-fluorophenyl)prop-2-enamide?
The molecular weight of (E)-N-(1H-benzimidazol-2-yl)-3-(4-fluorophenyl)prop-2-enamide is 281.10 g/mol.
Where can I buy (E)-N-(1H-benzimidazol-2-yl)-3-(4-fluorophenyl)prop-2-enamide?
You can request a quote for (E)-N-(1H-benzimidazol-2-yl)-3-(4-fluorophenyl)prop-2-enamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (E)-N-(1H-benzimidazol-2-yl)-3-(4-fluorophenyl)prop-2-enamide?
Yes, KEHONG BIO provides custom synthesis services for (E)-N-(1H-benzimidazol-2-yl)-3-(4-fluorophenyl)prop-2-enamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.