flunarizine
TL;DR: flunarizine (CAS 1164531-52-5) is a chemical compound with molecular formula C26H27ClF2N2 and molecular weight 440.18 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1-[bis(4-fluorophenyl)methyl]-4-[(E)-3-phenylprop-2-enyl]piperazine;hydrochloride
Also Known As: flunarizine, Flunarizine dihydrochloride, flunarizine hydrochloride, Pharmakon1600-01500993, 1-[Bis(4-fluorophenyl)methyl]-4-[(E)-3-phenylprop-2-enyl]piperazine;hydrochloride
| Molecular Formula | C26H27ClF2N2 |
|---|---|
| Molecular Weight | 440.18 g/mol |
| LogP | 5.807 |
| Topological Polar Surface Area | 6.48 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 6 |
| Exact Mass | 440.18307 |
| Heavy Atoms | 31 |
| Complexity | 905.46185 |
Chemical Identifiers
| CAS Number | 1164531-52-5 |
|---|---|
| SMILES | C1CN(CCN1C/C=C/C2=CC=CC=C2)C(C3=CC=C(C=C3)F)C4=CC=C(C=C4)F.Cl |
Product Overview
flunarizine (CAS 1164531-52-5), with molecular formula C26H27ClF2N2 and molecular weight 440.18 g/mol. IUPAC: 1-[bis(4-fluorophenyl)methyl]-4-[(E)-3-phenylprop-2-enyl]piperazine;hydrochloride.
Chemical Property Profile of flunarizine
Property Insights of flunarizine
The XLogP value of 5.807 indicates that flunarizine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 6.48 Ų, flunarizine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, flunarizine has 0 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of flunarizine?
The CAS number of flunarizine is 1164531-52-5.
What is the molecular formula of flunarizine?
The molecular formula of flunarizine is C26H27ClF2N2.
What is the molecular weight of flunarizine?
The molecular weight of flunarizine is 440.18 g/mol.
Where can I buy flunarizine?
You can request a quote for flunarizine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for flunarizine?
Yes, KEHONG BIO provides custom synthesis services for flunarizine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.