(E)-3-(2-Chloro-phenyl)-N-(4-methyl-pyridin-2-yl)-acrylamide
TL;DR: (E)-3-(2-Chloro-phenyl)-N-(4-methyl-pyridin-2-yl)-acrylamide (CAS 1164526-86-6) is a chemical compound with molecular formula C15H13ClN2O and molecular weight 272.07 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(E)-3-(2-chlorophenyl)-N-(4-methyl-2-pyridinyl)prop-2-enamide
Also Known As: (E)-3-(2-Chloro-phenyl)-N-(4-methyl-pyridin-2-yl)-acrylamide, (E)-3-(2-chlorophenyl)-N-(4-methylpyridin-2-yl)prop-2-enamide, (2E)-3-(2-chlorophenyl)-N-(4-methylpyridin-2-yl)prop-2-enamide, (E)-3-(2-chlorophenyl)-N-(4-methyl-2-pyridyl)acrylamide, (E)-3-(2-chlorophenyl)-N-(4-methylpyridin-2-yl)acrylamide
| Molecular Formula | C15H13ClN2O |
|---|---|
| Molecular Weight | 272.07 g/mol |
| LogP | 3.69532 |
| Topological Polar Surface Area | 41.99 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 3 |
| Exact Mass | 272.07166 |
| Heavy Atoms | 19 |
| Complexity | 623.04755 |
Chemical Identifiers
| CAS Number | 1164526-86-6 |
|---|---|
| SMILES | CC1=CC(=NC=C1)NC(=O)/C=C/C2=CC=CC=C2Cl |
Product Overview
(E)-3-(2-Chloro-phenyl)-N-(4-methyl-pyridin-2-yl)-acrylamide (CAS 1164526-86-6), with molecular formula C15H13ClN2O and molecular weight 272.07 g/mol. IUPAC: (E)-3-(2-chlorophenyl)-N-(4-methyl-2-pyridinyl)prop-2-enamide.
Chemical Property Profile of (E)-3-(2-Chloro-phenyl)-N-(4-methyl-pyridin-2-yl)-acrylamide
Property Insights of (E)-3-(2-Chloro-phenyl)-N-(4-methyl-pyridin-2-yl)-acrylamide
The XLogP value of 3.69532 indicates that (E)-3-(2-Chloro-phenyl)-N-(4-methyl-pyridin-2-yl)-acrylamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 41.99 Ų, (E)-3-(2-Chloro-phenyl)-N-(4-methyl-pyridin-2-yl)-acrylamide exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, (E)-3-(2-Chloro-phenyl)-N-(4-methyl-pyridin-2-yl)-acrylamide has 1 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (E)-3-(2-Chloro-phenyl)-N-(4-methyl-pyridin-2-yl)-acrylamide?
The CAS number of (E)-3-(2-Chloro-phenyl)-N-(4-methyl-pyridin-2-yl)-acrylamide is 1164526-86-6.
What is the molecular formula of (E)-3-(2-Chloro-phenyl)-N-(4-methyl-pyridin-2-yl)-acrylamide?
The molecular formula of (E)-3-(2-Chloro-phenyl)-N-(4-methyl-pyridin-2-yl)-acrylamide is C15H13ClN2O.
What is the molecular weight of (E)-3-(2-Chloro-phenyl)-N-(4-methyl-pyridin-2-yl)-acrylamide?
The molecular weight of (E)-3-(2-Chloro-phenyl)-N-(4-methyl-pyridin-2-yl)-acrylamide is 272.07 g/mol.
Where can I buy (E)-3-(2-Chloro-phenyl)-N-(4-methyl-pyridin-2-yl)-acrylamide?
You can request a quote for (E)-3-(2-Chloro-phenyl)-N-(4-methyl-pyridin-2-yl)-acrylamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (E)-3-(2-Chloro-phenyl)-N-(4-methyl-pyridin-2-yl)-acrylamide?
Yes, KEHONG BIO provides custom synthesis services for (E)-3-(2-Chloro-phenyl)-N-(4-methyl-pyridin-2-yl)-acrylamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.