![2-[[(E)-3-(4-tert-butylphenyl)prop-2-enoyl]amino]-N,N,4-trimethyl-1,3-thiazole-5-carboxamide structure](/static/products/1164/1164489-48-8.webp)
2-[[(E)-3-(4-tert-butylphenyl)prop-2-enoyl]amino]-N,N,4-trimethyl-1,3-thiazole-5-carboxamide
TL;DR: 2-[[(E)-3-(4-tert-butylphenyl)prop-2-enoyl]amino]-N,N,4-trimethyl-1,3-thiazole-5-carboxamide (CAS 1164489-48-8) is a chemical compound with molecular formula C20H25N3O2S and molecular weight 371.17 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-[[(E)-3-(4-tert-butylphenyl)prop-2-enoyl]amino]-N,N,4-trimethyl-1,3-thiazole-5-carboxamide
Also Known As: 2-[[(E)-3-(4-tert-butylphenyl)prop-2-enoyl]amino]-N,N,4-trimethyl-1,3-thiazole-5-carboxamide, 2-{[3-(4-tert-butylphenyl)acryloyl]amino}-N,N,4-trimethyl-1,3-thiazole-5-carboxamide, (2E)-N-[5-(N,N-dimethylcarbamoyl)-4-methyl(1,3-thiazol-2-yl)]-3-[4-(tert-butyl )phenyl]prop-2-enamide, 2-{[(2E)-3-(4-tert-butylphenyl)prop-2-enoyl]amino}-N,N,4-trimethyl-1,3-thiazole-5-carboxamide
| Molecular Formula | C20H25N3O2S |
|---|---|
| Molecular Weight | 371.17 g/mol |
| LogP | 4.10272 |
| Topological Polar Surface Area | 62.3 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 4 |
| Exact Mass | 371.16675 |
| Heavy Atoms | 26 |
| Complexity | 827.73145 |
Chemical Identifiers
| CAS Number | 1164489-48-8 |
|---|---|
| SMILES | CC1=C(SC(=N1)NC(=O)/C=C/C2=CC=C(C=C2)C(C)(C)C)C(=O)N(C)C |
Product Overview
2-[[(E)-3-(4-tert-butylphenyl)prop-2-enoyl]amino]-N,N,4-trimethyl-1,3-thiazole-5-carboxamide (CAS 1164489-48-8), with molecular formula C20H25N3O2S and molecular weight 371.17 g/mol. IUPAC: 2-[[(E)-3-(4-tert-butylphenyl)prop-2-enoyl]amino]-N,N,4-trimethyl-1,3-thiazole-5-carboxamide.
Chemical Property Profile of 2-[[(E)-3-(4-tert-butylphenyl)prop-2-enoyl]amino]-N,N,4-trimethyl-1,3-thiazole-5-carboxamide
Property Insights of 2-[[(E)-3-(4-tert-butylphenyl)prop-2-enoyl]amino]-N,N,4-trimethyl-1,3-thiazole-5-carboxamide
The XLogP value of 4.10272 indicates that 2-[[(E)-3-(4-tert-butylphenyl)prop-2-enoyl]amino]-N,N,4-trimethyl-1,3-thiazole-5-carboxamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 62.3 Ų falls within the moderate polarity range, balancing permeability and solubility for 2-[[(E)-3-(4-tert-butylphenyl)prop-2-enoyl]amino]-N,N,4-trimethyl-1,3-thiazole-5-carboxamide. Following Lipinski's Rule of Five, 2-[[(E)-3-(4-tert-butylphenyl)prop-2-enoyl]amino]-N,N,4-trimethyl-1,3-thiazole-5-carboxamide has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 2-[[(E)-3-(4-tert-butylphenyl)prop-2-enoyl]amino]-N,N,4-trimethyl-1,3-thiazole-5-carboxamide?
The CAS number of 2-[[(E)-3-(4-tert-butylphenyl)prop-2-enoyl]amino]-N,N,4-trimethyl-1,3-thiazole-5-carboxamide is 1164489-48-8.
What is the molecular formula of 2-[[(E)-3-(4-tert-butylphenyl)prop-2-enoyl]amino]-N,N,4-trimethyl-1,3-thiazole-5-carboxamide?
The molecular formula of 2-[[(E)-3-(4-tert-butylphenyl)prop-2-enoyl]amino]-N,N,4-trimethyl-1,3-thiazole-5-carboxamide is C20H25N3O2S.
What is the molecular weight of 2-[[(E)-3-(4-tert-butylphenyl)prop-2-enoyl]amino]-N,N,4-trimethyl-1,3-thiazole-5-carboxamide?
The molecular weight of 2-[[(E)-3-(4-tert-butylphenyl)prop-2-enoyl]amino]-N,N,4-trimethyl-1,3-thiazole-5-carboxamide is 371.17 g/mol.
Where can I buy 2-[[(E)-3-(4-tert-butylphenyl)prop-2-enoyl]amino]-N,N,4-trimethyl-1,3-thiazole-5-carboxamide?
You can request a quote for 2-[[(E)-3-(4-tert-butylphenyl)prop-2-enoyl]amino]-N,N,4-trimethyl-1,3-thiazole-5-carboxamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 2-[[(E)-3-(4-tert-butylphenyl)prop-2-enoyl]amino]-N,N,4-trimethyl-1,3-thiazole-5-carboxamide?
Yes, KEHONG BIO provides custom synthesis services for 2-[[(E)-3-(4-tert-butylphenyl)prop-2-enoyl]amino]-N,N,4-trimethyl-1,3-thiazole-5-carboxamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.