2-cyano-N-(2-methylphenyl)-3-(3-thienyl)acrylamide
TL;DR: 2-cyano-N-(2-methylphenyl)-3-(3-thienyl)acrylamide (CAS 1164475-97-1) is a chemical compound with molecular formula C15H12N2OS and molecular weight 268.07 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(Z)-2-cyano-N-(2-methylphenyl)-3-thiophen-3-ylprop-2-enamide
Also Known As: 2-cyano-N-(2-methylphenyl)-3-(3-thienyl)acrylamide, (Z)-2-cyano-N-(2-methylphenyl)-3-thiophen-3-ylprop-2-enamide, 2-cyano-N-(2-methylphenyl)-3-(thiophen-3-yl)prop-2-enamide
| Molecular Formula | C15H12N2OS |
|---|---|
| Molecular Weight | 268.07 g/mol |
| LogP | 3.6022 |
| Topological Polar Surface Area | 52.89 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 3 |
| Exact Mass | 268.06705 |
| Heavy Atoms | 19 |
| Complexity | 651.03516 |
Chemical Identifiers
| CAS Number | 1164475-97-1 |
|---|---|
| SMILES | CC1=CC=CC=C1NC(=O)/C(=C\C2=CSC=C2)/C#N |
Product Overview
2-cyano-N-(2-methylphenyl)-3-(3-thienyl)acrylamide (CAS 1164475-97-1), with molecular formula C15H12N2OS and molecular weight 268.07 g/mol. IUPAC: (Z)-2-cyano-N-(2-methylphenyl)-3-thiophen-3-ylprop-2-enamide.
Chemical Property Profile of 2-cyano-N-(2-methylphenyl)-3-(3-thienyl)acrylamide
Property Insights of 2-cyano-N-(2-methylphenyl)-3-(3-thienyl)acrylamide
The XLogP value of 3.6022 indicates that 2-cyano-N-(2-methylphenyl)-3-(3-thienyl)acrylamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 52.89 Ų, 2-cyano-N-(2-methylphenyl)-3-(3-thienyl)acrylamide exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 2-cyano-N-(2-methylphenyl)-3-(3-thienyl)acrylamide has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 2-cyano-N-(2-methylphenyl)-3-(3-thienyl)acrylamide?
The CAS number of 2-cyano-N-(2-methylphenyl)-3-(3-thienyl)acrylamide is 1164475-97-1.
What is the molecular formula of 2-cyano-N-(2-methylphenyl)-3-(3-thienyl)acrylamide?
The molecular formula of 2-cyano-N-(2-methylphenyl)-3-(3-thienyl)acrylamide is C15H12N2OS.
What is the molecular weight of 2-cyano-N-(2-methylphenyl)-3-(3-thienyl)acrylamide?
The molecular weight of 2-cyano-N-(2-methylphenyl)-3-(3-thienyl)acrylamide is 268.07 g/mol.
Where can I buy 2-cyano-N-(2-methylphenyl)-3-(3-thienyl)acrylamide?
You can request a quote for 2-cyano-N-(2-methylphenyl)-3-(3-thienyl)acrylamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 2-cyano-N-(2-methylphenyl)-3-(3-thienyl)acrylamide?
Yes, KEHONG BIO provides custom synthesis services for 2-cyano-N-(2-methylphenyl)-3-(3-thienyl)acrylamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.