Tulopafant
TL;DR: Tulopafant (CAS 116289-53-3) is a chemical compound with molecular formula C25H19N3O2S and molecular weight 425.12 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-(3-benzoylphenyl)-3-pyridin-3-yl-1,3-dihydropyrrolo[1,2-c][1,3]thiazole-7-carboxamide
Also Known As: Tulopafant, Tulopafantum, Tulopafant [INN], Tulopafantum [INN-Latin], PDSP1_000729
| Molecular Formula | C25H19N3O2S |
|---|---|
| Molecular Weight | 425.12 g/mol |
| LogP | 3.8 |
| Topological Polar Surface Area | 89.3 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 5 |
| Exact Mass | 425.1198 |
| Heavy Atoms | 31 |
| Complexity | 653.0 |
Chemical Identifiers
| CAS Number | 116289-53-3 |
|---|---|
| SMILES | C1C2=C(C=CN2C(S1)C3=CN=CC=C3)C(=O)NC4=CC=CC(=C4)C(=O)C5=CC=CC=C5 |
| InChIKey | PQQFNXGONTVQLM-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 2 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
Tulopafant (CAS 116289-53-3), with molecular formula C25H19N3O2S and molecular weight 425.12 g/mol. IUPAC: N-(3-benzoylphenyl)-3-pyridin-3-yl-1,3-dihydropyrrolo[1,2-c][1,3]thiazole-7-carboxamide.
Chemical Property Profile of Tulopafant
Property Insights of Tulopafant
The XLogP value of 3.8 indicates that Tulopafant is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 89.3 Ų falls within the moderate polarity range, balancing permeability and solubility for Tulopafant. Following Lipinski's Rule of Five, Tulopafant has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Tulopafant?
The CAS number of Tulopafant is 116289-53-3.
What is the molecular formula of Tulopafant?
The molecular formula of Tulopafant is C25H19N3O2S.
What is the molecular weight of Tulopafant?
The molecular weight of Tulopafant is 425.12 g/mol.
Where can I buy Tulopafant?
You can request a quote for Tulopafant directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Tulopafant?
Yes, KEHONG BIO provides custom synthesis services for Tulopafant and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.