(((2R,3S,5R)-5-(5-((E)-2-Bromo-vinyl)-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-3-hydroxy-tetrahydro-furan-2-ylmethoxy}-hydroxy-phosphoryl)-acetic acid ethyl ester
概要：(((2R,3S,5R)-5-(5-((E)-2-Bromo-vinyl)-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-3-hydroxy-tetrahydro-furan-2-ylmethoxy}-hydroxy-phosphoryl)-acetic acid ethyl ester（CAS 115365-28-1）是一种化学化合物，分子式为C15H20BrN2O9P，分子量为482.01 g/mol。河南科弘生物科技有限公司提供CRO/CDMO定制合成服务，支持克级到吨级规格。
[(2R,3S,5R)-5-[5-[(E)-2-bromoethenyl]-2,4-dioxopyrimidin-1-yl]-3-hydroxyoxolan-2-yl]methoxy-(2-ethoxy-2-oxoethyl)phosphinic acid
又称：(((2R,3S,5R)-5-(5-((E)-2-Bromo-vinyl)-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-3-hydroxy-tetrahydro-furan-2-ylmethoxy}-hydroxy-phosphoryl)-acetic acid ethyl ester, <(ethoxycarbonyl)methyl>phosphonic acid 5-(E)-(2-bromovinyl)-2'-deoxyuridin-5'-yl ester, [(ethoxycarbonyl)methyl]phosphonic acid 5-(E)-(2-bromovinyl)-2'-deoxyuridin-5'-yl ester, ({(2R,3S,5R)-5-[5-((E)-2-Bromo-vinyl)-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl]-3-hydroxy-tetrahydro-furan-2-ylmethoxy}-hydroxy-phosphoryl)-acetic acid ethyl ester, [(2R,3S,5R)-5-[5-[(E)-2-bromoethenyl]-2,4-dioxopyrimidin-1-yl]-3-hydroxyoxolan-2-yl]methoxy-(2-ethoxy-2-oxoethyl)phosphinic acid
| 分子式 | C15H20BrN2O9P |
|---|---|
| 分子量 | 482.01 g/mol |
| LogP | 0.3157 |
| 拓扑极性表面积 | 157.15 Ų |
| 氢键供体数 | 3 |
| 氢键受体数 | 8 |
| 可旋转键数 | 8 |
| 精确质量 | 482.00897 |
| 重原子数 | 28 |
| 复杂度 | 896.23315 |
化学标识符
| CAS 编号 | 115365-28-1 |
|---|---|
| SMILES | CCOC(=O)CP(=O)(O)OC[C@@H]1[C@H](C[C@@H](O1)N2C=C(C(=O)NC2=O)/C=C/Br)O |
产品概述
(((2R,3S,5R)-5-(5-((E)-2-Bromo-vinyl)-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-3-hydroxy-tetrahydro-furan-2-ylmethoxy}-hydroxy-phosphoryl)-acetic acid ethyl ester（CAS 115365-28-1），分子式为C15H20BrN2O9P，分子量为482.01 g/mol。IUPAC名：[(2R,3S,5R)-5-[5-[(E)-2-bromoethenyl]-2,4-dioxopyrimidin-1-yl]-3-hydroxyoxolan-2-yl]methoxy-(2-ethoxy-2-oxoethyl)phosphinic acid。
(((2R,3S,5R)-5-(5-((E)-2-Bromo-vinyl)-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-3-hydroxy-tetrahydro-furan-2-ylmethoxy}-hydroxy-phosphoryl)-acetic acid ethyl ester化学性质概览
属性洞察：(((2R,3S,5R)-5-(5-((E)-2-Bromo-vinyl)-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-3-hydroxy-tetrahydro-furan-2-ylmethoxy}-hydroxy-phosphoryl)-acetic acid ethyl ester
(((2R,3S,5R)-5-(5-((E)-2-Bromo-vinyl)-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-3-hydroxy-tetrahydro-furan-2-ylmethoxy}-hydroxy-phosphoryl)-acetic acid ethyl ester的XLogP值为0.3157，表明具有中等亲脂性，在水溶性和膜透过性之间取得平衡。 TPSA为157.15 Ų，极性较高，提示该化合物膜透过性可能受限但水溶性较好。 根据Lipinski五规则，(((2R,3S,5R)-5-(5-((E)-2-Bromo-vinyl)-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-3-hydroxy-tetrahydro-furan-2-ylmethoxy}-hydroxy-phosphoryl)-acetic acid ethyl ester有3个氢键供体和8个氢键受体，均在类药范围内，提示具有较好的口服生物利用度潜力。
常见问题
常见问题
(((2R,3S,5R)-5-(5-((E)-2-Bromo-vinyl)-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-3-hydroxy-tetrahydro-furan-2-ylmethoxy}-hydroxy-phosphoryl)-acetic acid ethyl ester的CAS号是多少？
(((2R,3S,5R)-5-(5-((E)-2-Bromo-vinyl)-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-3-hydroxy-tetrahydro-furan-2-ylmethoxy}-hydroxy-phosphoryl)-acetic acid ethyl ester的CAS号为115365-28-1。
(((2R,3S,5R)-5-(5-((E)-2-Bromo-vinyl)-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-3-hydroxy-tetrahydro-furan-2-ylmethoxy}-hydroxy-phosphoryl)-acetic acid ethyl ester的分子式是什么？
(((2R,3S,5R)-5-(5-((E)-2-Bromo-vinyl)-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-3-hydroxy-tetrahydro-furan-2-ylmethoxy}-hydroxy-phosphoryl)-acetic acid ethyl ester的分子式为C15H20BrN2O9P。
(((2R,3S,5R)-5-(5-((E)-2-Bromo-vinyl)-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-3-hydroxy-tetrahydro-furan-2-ylmethoxy}-hydroxy-phosphoryl)-acetic acid ethyl ester的分子量是多少？
(((2R,3S,5R)-5-(5-((E)-2-Bromo-vinyl)-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-3-hydroxy-tetrahydro-furan-2-ylmethoxy}-hydroxy-phosphoryl)-acetic acid ethyl ester的分子量为482.01 g/mol。
在哪里可以购买(((2R,3S,5R)-5-(5-((E)-2-Bromo-vinyl)-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-3-hydroxy-tetrahydro-furan-2-ylmethoxy}-hydroxy-phosphoryl)-acetic acid ethyl ester？
您可以直接向科弘生物询价(((2R,3S,5R)-5-(5-((E)-2-Bromo-vinyl)-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-3-hydroxy-tetrahydro-furan-2-ylmethoxy}-hydroxy-phosphoryl)-acetic acid ethyl ester。联系我们或发送邮件至info@kehongbio.com获取报价和库存信息。
科弘生物是否提供(((2R,3S,5R)-5-(5-((E)-2-Bromo-vinyl)-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-3-hydroxy-tetrahydro-furan-2-ylmethoxy}-hydroxy-phosphoryl)-acetic acid ethyl ester的定制合成服务？
是的，科弘生物提供(((2R,3S,5R)-5-(5-((E)-2-Bromo-vinyl)-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-3-hydroxy-tetrahydro-furan-2-ylmethoxy}-hydroxy-phosphoryl)-acetic acid ethyl ester及相关化合物的定制合成服务。请联系我们并告知您的具体需求，包括数量、纯度和交期。