5-(N-tert-Butyl)amiloride
TL;DR: 5-(N-tert-Butyl)amiloride (CAS 1152-29-0) is a chemical compound with molecular formula C10H16ClN7O and molecular weight 285.11 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
3-amino-5-(tert-butylamino)-6-chloro-N-(diaminomethylidene)pyrazine-2-carboxamide
Also Known As: 5-N-t-Butylamiloride, Butylamirolide, 5-(N-tert-Butyl)amiloride, 3-amino-5-(tert-butylamino)-6-chloro-N-(diaminomethylidene)pyrazine-2-carboxamide, Pyrazinecarboxamide, 3-amino-N-(aminoiminomethyl)-6-chloro-5-((1,1-dimethylethyl)amino)-
| Molecular Formula | C10H16ClN7O |
|---|---|
| Molecular Weight | 285.11 g/mol |
| LogP | 0.3362 |
| Topological Polar Surface Area | 145.3 Ų |
| Hydrogen Bond Donors | 4 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 2 |
| Exact Mass | 285.11047 |
| Heavy Atoms | 19 |
| Complexity | 531.4151 |
Chemical Identifiers
| CAS Number | 1152-29-0 |
|---|---|
| SMILES | CC(C)(C)NC1=NC(=C(N=C1Cl)C(=O)N=C(N)N)N |
Product Overview
5-(N-tert-Butyl)amiloride (CAS 1152-29-0), with molecular formula C10H16ClN7O and molecular weight 285.11 g/mol. IUPAC: 3-amino-5-(tert-butylamino)-6-chloro-N-(diaminomethylidene)pyrazine-2-carboxamide.
Chemical Property Profile of 5-(N-tert-Butyl)amiloride
Property Insights of 5-(N-tert-Butyl)amiloride
The XLogP value of 0.3362 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 5-(N-tert-Butyl)amiloride. The TPSA of 145.3 Ų indicates high polarity, suggesting 5-(N-tert-Butyl)amiloride may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, 5-(N-tert-Butyl)amiloride has 4 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 5-(N-tert-Butyl)amiloride?
The CAS number of 5-(N-tert-Butyl)amiloride is 1152-29-0.
What is the molecular formula of 5-(N-tert-Butyl)amiloride?
The molecular formula of 5-(N-tert-Butyl)amiloride is C10H16ClN7O.
What is the molecular weight of 5-(N-tert-Butyl)amiloride?
The molecular weight of 5-(N-tert-Butyl)amiloride is 285.11 g/mol.
Where can I buy 5-(N-tert-Butyl)amiloride?
You can request a quote for 5-(N-tert-Butyl)amiloride directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 5-(N-tert-Butyl)amiloride?
Yes, KEHONG BIO provides custom synthesis services for 5-(N-tert-Butyl)amiloride and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.