Cyclosporin lactam(3,4)
TL;DR: Cyclosporin lactam(3,4) (CAS 115141-85-0) is a chemical compound with molecular formula C64H113N11O12 and molecular weight 1227.86 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
29-ethyl-26-[(E)-1-hydroxy-2-methylhex-4-enyl]-7,11,14,16,19,22,25,31-octamethyl-2,8,17,20-tetrakis(2-methylpropyl)-5,23-di(propan-2-yl)-1,4,7,10,13,16,19,22,25,28,31-undecazabicyclo[30.3.1]hexatriacontane-3,6,9,12,15,18,21,24,27,30,36-undecone
Also Known As: Cyclosporin lactam(3,4), Cyclosporin AM 8, H-D-Thr(tBu)-OMe, 29-ethyl-26-[(E)-1-hydroxy-2-methylhex-4-enyl]-7,11,14,16,19,22,25,31-octamethyl-2,8,17,20-tetrakis(2-methylpropyl)-5,23-di(propan-2-yl)-1,4,7,10,13,16,19,22,25,28,31-undecazabicyclo[30.3.1]hexatriacontane-3,6,9,12,15,18,21,24,27,30,36-undecone, 8-((S-(R*,R*))-N-Methyl-alpha-(2-methylpropyl)-2-oxo-3-amino-1-piperidineacetic acid)-9-de(N-methyl-L-leucine)cyclosporin A
| Molecular Formula | C64H113N11O12 |
|---|---|
| Molecular Weight | 1227.86 g/mol |
| LogP | 3.8016 |
| Topological Polar Surface Area | 278.8 Ų |
| Hydrogen Bond Donors | 5 |
| Hydrogen Bond Acceptors | 12 |
| Rotatable Bonds | 15 |
| Exact Mass | 1227.857 |
| Heavy Atoms | 87 |
| Complexity | 2413.5742 |
Chemical Identifiers
| CAS Number | 115141-85-0 |
|---|---|
| SMILES | CCC1C(=O)N(C2CCCN(C2=O)C(C(=O)NC(C(=O)N(C(C(=O)NC(C(=O)NC(C(=O)N(C(C(=O)N(C(C(=O)N(C(C(=O)N(C(C(=O)N1)C(C(C)C/C=C/C)O)C)C(C)C)C)CC(C)C)C)CC(C)C)C)C)C)CC(C)C)C)C(C)C)CC(C)C)C |
Product Overview
Cyclosporin lactam(3,4) (CAS 115141-85-0), with molecular formula C64H113N11O12 and molecular weight 1227.86 g/mol. IUPAC: 29-ethyl-26-[(E)-1-hydroxy-2-methylhex-4-enyl]-7,11,14,16,19,22,25,31-octamethyl-2,8,17,20-tetrakis(2-methylpropyl)-5,23-di(propan-2-yl)-1,4,7,10,13,16,19,22,25,28,31-undecazabicyclo[30.3.1]hexatriacontane-3,6,9,12,15,18,21,24,27,30,36-undecone.
Chemical Property Profile of Cyclosporin lactam(3,4)
Property Insights of Cyclosporin lactam(3,4)
The XLogP value of 3.8016 indicates that Cyclosporin lactam(3,4) is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 278.8 Ų indicates high polarity, suggesting Cyclosporin lactam(3,4) may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Cyclosporin lactam(3,4) has 5 hydrogen bond donor(s) and 12 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Cyclosporin lactam(3,4)?
The CAS number of Cyclosporin lactam(3,4) is 115141-85-0.
What is the molecular formula of Cyclosporin lactam(3,4)?
The molecular formula of Cyclosporin lactam(3,4) is C64H113N11O12.
What is the molecular weight of Cyclosporin lactam(3,4)?
The molecular weight of Cyclosporin lactam(3,4) is 1227.86 g/mol.
Where can I buy Cyclosporin lactam(3,4)?
You can request a quote for Cyclosporin lactam(3,4) directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Cyclosporin lactam(3,4)?
Yes, KEHONG BIO provides custom synthesis services for Cyclosporin lactam(3,4) and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.