4-Chloro-N-methylpicolinamide structure

4-Chloro-N-methylpicolinamide

TL;DR: 4-Chloro-N-methylpicolinamide (CAS 114780-06-2) is a chemical compound with molecular formula C7H7ClN2O and molecular weight 170.02 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

4-chloro-N-methylpyridine-2-carboxamide

Also Known As: 4-Chloro-N-methylpicolinamide, 4-Chloro-N-methylpyridine-2-carboxamide, N-Methyl-4-chloropyridine-2-carboxamide, 4-Chloro-N-methyl-2-pyridinecarboxamide, Sorafenib Impurity 2

CAS: 114780-06-2
Molecular Formula C7H7ClN2O
Molecular Weight 170.02 g/mol
LogP 1.0946
Topological Polar Surface Area 41.99 Ų
Hydrogen Bond Donors 1
Hydrogen Bond Acceptors 2
Rotatable Bonds 1
Exact Mass 170.02469
Heavy Atoms 11
Complexity 274.898

Chemical Identifiers

CAS Number 114780-06-2
SMILES CNC(=O)C1=NC=CC(=C1)Cl

Product Overview

4-Chloro-N-methylpicolinamide (CAS 114780-06-2), with molecular formula C7H7ClN2O and molecular weight 170.02 g/mol. IUPAC: 4-chloro-N-methylpyridine-2-carboxamide.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of 4-Chloro-N-methylpicolinamide

XLogP
1.0946
TPSA (Topological Polar Surface Area)
41.99
Hydrogen Bond Donors
1
Hydrogen Bond Acceptors
2
Rotatable Bonds
1
Heavy Atoms
11
Complexity
274.898
Exact Mass
170.02469
Monoisotopic Mass
170.02469
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of 4-Chloro-N-methylpicolinamide

The XLogP value of 1.0946 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 4-Chloro-N-methylpicolinamide. With a topological polar surface area (TPSA) of 41.99 Ų, 4-Chloro-N-methylpicolinamide exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 4-Chloro-N-methylpicolinamide has 1 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of 4-Chloro-N-methylpicolinamide?

The CAS number of 4-Chloro-N-methylpicolinamide is 114780-06-2.

What is the molecular formula of 4-Chloro-N-methylpicolinamide?

The molecular formula of 4-Chloro-N-methylpicolinamide is C7H7ClN2O.

What is the molecular weight of 4-Chloro-N-methylpicolinamide?

The molecular weight of 4-Chloro-N-methylpicolinamide is 170.02 g/mol.

Where can I buy 4-Chloro-N-methylpicolinamide?

You can request a quote for 4-Chloro-N-methylpicolinamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for 4-Chloro-N-methylpicolinamide?

Yes, KEHONG BIO provides custom synthesis services for 4-Chloro-N-methylpicolinamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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