![2-{4-[(Tert-butyldimethylsilyl)oxy]phenyl}acetic acid structure](/static/products/1147/114774-40-2.webp)
2-{4-[(Tert-butyldimethylsilyl)oxy]phenyl}acetic acid
TL;DR: 2-{4-[(Tert-butyldimethylsilyl)oxy]phenyl}acetic acid (CAS 114774-40-2) is a chemical compound with molecular formula C14H22O3Si and molecular weight 266.13 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-[4-[tert-butyl(dimethyl)silyl]oxyphenyl]acetic acid
Also Known As: 2-{4-[(tert-butyldimethylsilyl)oxy]phenyl}acetic acid, 2-(4-((tert-butyldimethylsilyl)oxy)phenyl)acetic acid, 4-(tert-Butyldimethylsiloxy)benzeneacetic acid, 4-Hydroxybenzeneacetic acid, TBDMS derivative, J1.496.225E
| Molecular Formula | C14H22O3Si |
|---|---|
| Molecular Weight | 266.13 g/mol |
| LogP | 3.6977 |
| Topological Polar Surface Area | 46.5 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 5 |
| Exact Mass | 266.13382 |
| Heavy Atoms | 18 |
| Complexity | 286.0 |
Chemical Identifiers
| CAS Number | 114774-40-2 |
|---|---|
| SMILES | CC(C)(C)[Si](C)(C)OC1=CC=C(C=C1)CC(=O)O |
| InChIKey | HFGPEISRKIZIHV-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 3 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
2-{4-[(Tert-butyldimethylsilyl)oxy]phenyl}acetic acid (CAS 114774-40-2), with molecular formula C14H22O3Si and molecular weight 266.13 g/mol. IUPAC: 2-[4-[tert-butyl(dimethyl)silyl]oxyphenyl]acetic acid.
Chemical Property Profile of 2-{4-[(Tert-butyldimethylsilyl)oxy]phenyl}acetic acid
Property Insights of 2-{4-[(Tert-butyldimethylsilyl)oxy]phenyl}acetic acid
The XLogP value of 3.6977 indicates that 2-{4-[(Tert-butyldimethylsilyl)oxy]phenyl}acetic acid is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 46.5 Ų, 2-{4-[(Tert-butyldimethylsilyl)oxy]phenyl}acetic acid exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 2-{4-[(Tert-butyldimethylsilyl)oxy]phenyl}acetic acid has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 2-{4-[(Tert-butyldimethylsilyl)oxy]phenyl}acetic acid?
The CAS number of 2-{4-[(Tert-butyldimethylsilyl)oxy]phenyl}acetic acid is 114774-40-2.
What is the molecular formula of 2-{4-[(Tert-butyldimethylsilyl)oxy]phenyl}acetic acid?
The molecular formula of 2-{4-[(Tert-butyldimethylsilyl)oxy]phenyl}acetic acid is C14H22O3Si.
What is the molecular weight of 2-{4-[(Tert-butyldimethylsilyl)oxy]phenyl}acetic acid?
The molecular weight of 2-{4-[(Tert-butyldimethylsilyl)oxy]phenyl}acetic acid is 266.13 g/mol.
Where can I buy 2-{4-[(Tert-butyldimethylsilyl)oxy]phenyl}acetic acid?
You can request a quote for 2-{4-[(Tert-butyldimethylsilyl)oxy]phenyl}acetic acid directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 2-{4-[(Tert-butyldimethylsilyl)oxy]phenyl}acetic acid?
Yes, KEHONG BIO provides custom synthesis services for 2-{4-[(Tert-butyldimethylsilyl)oxy]phenyl}acetic acid and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.