26,26,26,27,27,27-Hexafluoro-1,23,25-trihydroxyvitamin D3 structure

26,26,26,27,27,27-Hexafluoro-1,23,25-trihydroxyvitamin D3

TL;DR: 26,26,26,27,27,27-Hexafluoro-1,23,25-trihydroxyvitamin D3 (CAS 114489-80-4) is a chemical compound with molecular formula C27H38F6O4 and molecular weight 540.27 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

(1R,5Z)-5-[(2E)-2-[(1R,7aR)-7a-methyl-1-[(2R)-7,7,7-trifluoro-4,6-dihydroxy-6-(trifluoromethyl)heptan-2-yl]-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidenecyclohexane-1,3-diol

Also Known As: 26-HFTH-vitamin D3, 5H,6H-PERFLUORODEC-5-ENE, 26,26,26,27,27,27-Hexafluoro-1,23,25-trihydroxyvitamin D3, (1R,5Z)-5-[(2E)-2-[(1R,7aR)-7a-methyl-1-[(2R)-7,7,7-trifluoro-4,6-dihydroxy-6-(trifluoromethyl)heptan-2-yl]-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidenecyclohexane-1,3-diol, 26,26,26,27,27,27-hexafluoro-1alpha,23S,25-trihydroxyvitamin D3

CAS: 114489-80-4
Molecular Formula C27H38F6O4
Molecular Weight 540.27 g/mol
LogP 5.7603
Topological Polar Surface Area 80.92 Ų
Hydrogen Bond Donors 4
Hydrogen Bond Acceptors 4
Rotatable Bonds 6
Exact Mass 540.26746
Heavy Atoms 37
Complexity 893.55286

Chemical Identifiers

CAS Number 114489-80-4
SMILES C[C@H](CC(CC(C(F)(F)F)(C(F)(F)F)O)O)[C@H]1CCC\2[C@@]1(CCC/C2=C\C=C/3\C[C@H](CC(C3=C)O)O)C

Product Overview

26,26,26,27,27,27-Hexafluoro-1,23,25-trihydroxyvitamin D3 (CAS 114489-80-4), with molecular formula C27H38F6O4 and molecular weight 540.27 g/mol. IUPAC: (1R,5Z)-5-[(2E)-2-[(1R,7aR)-7a-methyl-1-[(2R)-7,7,7-trifluoro-4,6-dihydroxy-6-(trifluoromethyl)heptan-2-yl]-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidenecyclohexane-1,3-diol.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
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Chemical Property Profile of 26,26,26,27,27,27-Hexafluoro-1,23,25-trihydroxyvitamin D3

XLogP
5.7603
TPSA (Topological Polar Surface Area)
80.92
Hydrogen Bond Donors
4
Hydrogen Bond Acceptors
4
Rotatable Bonds
6
Heavy Atoms
37
Complexity
893.55286
Exact Mass
540.26746
Monoisotopic Mass
540.26746
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of 26,26,26,27,27,27-Hexafluoro-1,23,25-trihydroxyvitamin D3

The XLogP value of 5.7603 indicates that 26,26,26,27,27,27-Hexafluoro-1,23,25-trihydroxyvitamin D3 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 80.92 Ų falls within the moderate polarity range, balancing permeability and solubility for 26,26,26,27,27,27-Hexafluoro-1,23,25-trihydroxyvitamin D3. Following Lipinski's Rule of Five, 26,26,26,27,27,27-Hexafluoro-1,23,25-trihydroxyvitamin D3 has 4 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of 26,26,26,27,27,27-Hexafluoro-1,23,25-trihydroxyvitamin D3?

The CAS number of 26,26,26,27,27,27-Hexafluoro-1,23,25-trihydroxyvitamin D3 is 114489-80-4.

What is the molecular formula of 26,26,26,27,27,27-Hexafluoro-1,23,25-trihydroxyvitamin D3?

The molecular formula of 26,26,26,27,27,27-Hexafluoro-1,23,25-trihydroxyvitamin D3 is C27H38F6O4.

What is the molecular weight of 26,26,26,27,27,27-Hexafluoro-1,23,25-trihydroxyvitamin D3?

The molecular weight of 26,26,26,27,27,27-Hexafluoro-1,23,25-trihydroxyvitamin D3 is 540.27 g/mol.

Where can I buy 26,26,26,27,27,27-Hexafluoro-1,23,25-trihydroxyvitamin D3?

You can request a quote for 26,26,26,27,27,27-Hexafluoro-1,23,25-trihydroxyvitamin D3 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for 26,26,26,27,27,27-Hexafluoro-1,23,25-trihydroxyvitamin D3?

Yes, KEHONG BIO provides custom synthesis services for 26,26,26,27,27,27-Hexafluoro-1,23,25-trihydroxyvitamin D3 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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