西多福韋
TL;DR: 西多福韋 (CAS 113852-37-2) is a chemical compound with molecular formula C8H14N3O6P and molecular weight 279.06 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
西多福韋
[(2S)-1-(4-amino-2-oxopyrimidin-1-yl)-3-hydroxypropan-2-yl]oxymethylphosphonic acid
Also Known As: Cidofovir, Vistide, HPMPC, Cidofovir anhydrous, anhydrous cidofovir
| Molecular Formula | C8H14N3O6P |
|---|---|
| Molecular Weight | 279.06 g/mol |
| LogP | -3.6 |
| Topological Polar Surface Area | 146.0 Ų |
| Hydrogen Bond Donors | 4 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 6 |
| Exact Mass | 279.062 |
| Heavy Atoms | 18 |
| Complexity | 417.0 |
| Melting Point | 480 |
| Solubility | =170 mg/mL at pH 6-8 |
Chemical Identifiers
| CAS Number | 113852-37-2 |
|---|---|
| SMILES | C1=CN(C(=O)N=C1N)C[C@@H](CO)OCP(=O)(O)O |
| InChIKey | VWFCHDSQECPREK-LURJTMIESA-N |
Patent-Derived Application Labels
Derived from 13 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
西多福韋 (CAS 113852-37-2), with molecular formula C8H14N3O6P and molecular weight 279.06 g/mol. IUPAC: [(2S)-1-(4-amino-2-oxopyrimidin-1-yl)-3-hydroxypropan-2-yl]oxymethylphosphonic acid.
Chemical Property Profile of 西多福韋
Property Insights of 西多福韋
The XLogP value of -3.6 indicates that 西多福韋 is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 146.0 Ų indicates high polarity, suggesting 西多福韋 may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, 西多福韋 has 4 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 西多福韋?
The CAS number of 西多福韋 is 113852-37-2.
What is the molecular formula of 西多福韋?
The molecular formula of 西多福韋 is C8H14N3O6P.
What is the molecular weight of 西多福韋?
The molecular weight of 西多福韋 is 279.06 g/mol.
Where can I buy 西多福韋?
You can request a quote for 西多福韋 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 西多福韋?
Yes, KEHONG BIO provides custom synthesis services for 西多福韋 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.