4-(Chloromethyl)-2-(4-fluorophenyl)-1,3-thiazole
TL;DR: 4-(Chloromethyl)-2-(4-fluorophenyl)-1,3-thiazole (CAS 113264-13-4) is a chemical compound with molecular formula C10H7ClFNS and molecular weight 227.00 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
4-(chloromethyl)-2-(4-fluorophenyl)-1,3-thiazole
Also Known As: 4-(chloromethyl)-2-(4-fluorophenyl)-1,3-thiazole, 4-(CHLOROMETHYL)-2-(4-FLUOROPHENYL)THIAZOLE, Thiazole, 4-(chloromethyl)-2-(4-fluorophenyl)-, 2,6-Dimethyl-1H-indole-3-carbaldehyde, 4-chloromethyl-2-(4-fluorophenyl)thiazole
| Molecular Formula | C10H7ClFNS |
|---|---|
| Molecular Weight | 227.00 g/mol |
| LogP | 3.688 |
| Topological Polar Surface Area | 12.89 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 2 |
| Exact Mass | 226.99718 |
| Heavy Atoms | 14 |
| Complexity | 423.942 |
Chemical Identifiers
| CAS Number | 113264-13-4 |
|---|---|
| SMILES | C1=CC(=CC=C1C2=NC(=CS2)CCl)F |
Product Overview
4-(Chloromethyl)-2-(4-fluorophenyl)-1,3-thiazole (CAS 113264-13-4), with molecular formula C10H7ClFNS and molecular weight 227.00 g/mol. IUPAC: 4-(chloromethyl)-2-(4-fluorophenyl)-1,3-thiazole.
Chemical Property Profile of 4-(Chloromethyl)-2-(4-fluorophenyl)-1,3-thiazole
Property Insights of 4-(Chloromethyl)-2-(4-fluorophenyl)-1,3-thiazole
The XLogP value of 3.688 indicates that 4-(Chloromethyl)-2-(4-fluorophenyl)-1,3-thiazole is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 12.89 Ų, 4-(Chloromethyl)-2-(4-fluorophenyl)-1,3-thiazole exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 4-(Chloromethyl)-2-(4-fluorophenyl)-1,3-thiazole has 0 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 4-(Chloromethyl)-2-(4-fluorophenyl)-1,3-thiazole?
The CAS number of 4-(Chloromethyl)-2-(4-fluorophenyl)-1,3-thiazole is 113264-13-4.
What is the molecular formula of 4-(Chloromethyl)-2-(4-fluorophenyl)-1,3-thiazole?
The molecular formula of 4-(Chloromethyl)-2-(4-fluorophenyl)-1,3-thiazole is C10H7ClFNS.
What is the molecular weight of 4-(Chloromethyl)-2-(4-fluorophenyl)-1,3-thiazole?
The molecular weight of 4-(Chloromethyl)-2-(4-fluorophenyl)-1,3-thiazole is 227.00 g/mol.
Where can I buy 4-(Chloromethyl)-2-(4-fluorophenyl)-1,3-thiazole?
You can request a quote for 4-(Chloromethyl)-2-(4-fluorophenyl)-1,3-thiazole directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 4-(Chloromethyl)-2-(4-fluorophenyl)-1,3-thiazole?
Yes, KEHONG BIO provides custom synthesis services for 4-(Chloromethyl)-2-(4-fluorophenyl)-1,3-thiazole and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.