4-Chloro-2-(4-fluorophenyl)quinazoline
TL;DR: 4-Chloro-2-(4-fluorophenyl)quinazoline (CAS 113242-33-4) is a chemical compound with molecular formula C14H8ClFN2 and molecular weight 258.04 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
4-chloro-2-(4-fluorophenyl)quinazoline
Also Known As: 4-chloro-2-(4-fluorophenyl)quinazoline, 4-CHLORO-2-(4-FLUORO-PHENYL)-QUINAZOLINE, 2-CYCLOPENTENE-1-CARBOXAMIDE, 2751AJ, Quinazoline,4-chloro-2-(4-fluorophenyl)-
| Molecular Formula | C14H8ClFN2 |
|---|---|
| Molecular Weight | 258.04 g/mol |
| LogP | 4.0893 |
| Topological Polar Surface Area | 25.78 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 1 |
| Exact Mass | 258.036 |
| Heavy Atoms | 18 |
| Complexity | 710.56586 |
Chemical Identifiers
| CAS Number | 113242-33-4 |
|---|---|
| SMILES | C1=CC=C2C(=C1)C(=NC(=N2)C3=CC=C(C=C3)F)Cl |
Product Overview
4-Chloro-2-(4-fluorophenyl)quinazoline (CAS 113242-33-4), with molecular formula C14H8ClFN2 and molecular weight 258.04 g/mol. IUPAC: 4-chloro-2-(4-fluorophenyl)quinazoline.
Chemical Property Profile of 4-Chloro-2-(4-fluorophenyl)quinazoline
Property Insights of 4-Chloro-2-(4-fluorophenyl)quinazoline
The XLogP value of 4.0893 indicates that 4-Chloro-2-(4-fluorophenyl)quinazoline is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 25.78 Ų, 4-Chloro-2-(4-fluorophenyl)quinazoline exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 4-Chloro-2-(4-fluorophenyl)quinazoline has 0 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 4-Chloro-2-(4-fluorophenyl)quinazoline?
The CAS number of 4-Chloro-2-(4-fluorophenyl)quinazoline is 113242-33-4.
What is the molecular formula of 4-Chloro-2-(4-fluorophenyl)quinazoline?
The molecular formula of 4-Chloro-2-(4-fluorophenyl)quinazoline is C14H8ClFN2.
What is the molecular weight of 4-Chloro-2-(4-fluorophenyl)quinazoline?
The molecular weight of 4-Chloro-2-(4-fluorophenyl)quinazoline is 258.04 g/mol.
Where can I buy 4-Chloro-2-(4-fluorophenyl)quinazoline?
You can request a quote for 4-Chloro-2-(4-fluorophenyl)quinazoline directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 4-Chloro-2-(4-fluorophenyl)quinazoline?
Yes, KEHONG BIO provides custom synthesis services for 4-Chloro-2-(4-fluorophenyl)quinazoline and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.