Amifostine Trihydrate structure

Amifostine Trihydrate

TL;DR: Amifostine Trihydrate (CAS 112901-68-5) is a chemical compound with molecular formula C5H21N2O6PS and molecular weight 268.09 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

2-(3-aminopropylamino)ethylsulfanylphosphonic acid;trihydrate

Also Known As: Amifostine trihydrate, amifostine, Ethyol, Amifostine hydrate, Anifostine trihydrate

CAS: 112901-68-5
Molecular Formula C5H21N2O6PS
Molecular Weight 268.09 g/mol
LogP -2.7234
Topological Polar Surface Area 124.0 Ų
Hydrogen Bond Donors 7
Hydrogen Bond Acceptors 9
Rotatable Bonds 7
Exact Mass 268.0858
Heavy Atoms 15
Complexity 152.0

Chemical Identifiers

CAS Number 112901-68-5
SMILES C(CN)CNCCSP(=O)(O)O.O.O.O
InChIKey TXQPXJKRNHJWAX-UHFFFAOYSA-N

Patent-Derived Application Labels

Derived from 3 IPC patent classification(s) across the SureChEMBL global patent database.

Agrochemicals (7 patents) Organometallic Reagents (13 patents) Pharmaceutical Intermediates (38 patents)

Product Overview

Amifostine Trihydrate (CAS 112901-68-5), with molecular formula C5H21N2O6PS and molecular weight 268.09 g/mol. IUPAC: 2-(3-aminopropylamino)ethylsulfanylphosphonic acid;trihydrate.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Amifostine Trihydrate

XLogP
-2.7234
TPSA (Topological Polar Surface Area)
124.0
Hydrogen Bond Donors
7
Hydrogen Bond Acceptors
9
Rotatable Bonds
7
Heavy Atoms
15
Complexity
152.0
Exact Mass
268.0858
Monoisotopic Mass
268.0858
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Amifostine Trihydrate

The XLogP value of -2.7234 indicates that Amifostine Trihydrate is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 124.0 Ų falls within the moderate polarity range, balancing permeability and solubility for Amifostine Trihydrate. Following Lipinski's Rule of Five, Amifostine Trihydrate has 7 hydrogen bond donor(s) and 9 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Amifostine Trihydrate?

The CAS number of Amifostine Trihydrate is 112901-68-5.

What is the molecular formula of Amifostine Trihydrate?

The molecular formula of Amifostine Trihydrate is C5H21N2O6PS.

What is the molecular weight of Amifostine Trihydrate?

The molecular weight of Amifostine Trihydrate is 268.09 g/mol.

Where can I buy Amifostine Trihydrate?

You can request a quote for Amifostine Trihydrate directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Amifostine Trihydrate?

Yes, KEHONG BIO provides custom synthesis services for Amifostine Trihydrate and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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