Rotigotine, (+)- structure

Rotigotine, (+)-

TL;DR: Rotigotine, (+)- (CAS 112835-48-0) is a chemical compound with molecular formula C19H25NOS and molecular weight 315.17 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

(6R)-6-[propyl(2-thiophen-2-ylethyl)amino]-5,6,7,8-tetrahydronaphthalen-1-ol

Also Known As: ent-Rotigotine, (+)-Rotigotine, Rotigotine, Rotigotine, (+)-, R-ROTIGOTINE

CAS: 112835-48-0
Molecular Formula C19H25NOS
Molecular Weight 315.17 g/mol
LogP 4.2657
Topological Polar Surface Area 23.47 Ų
Hydrogen Bond Donors 1
Hydrogen Bond Acceptors 3
Rotatable Bonds 6
Exact Mass 315.16568
Heavy Atoms 22
Complexity 593.4876

Chemical Identifiers

CAS Number 112835-48-0
SMILES CCCN(CCC1=CC=CS1)[C@@H]2CCC3=C(C2)C=CC=C3O

Product Overview

Rotigotine, (+)- (CAS 112835-48-0), with molecular formula C19H25NOS and molecular weight 315.17 g/mol. IUPAC: (6R)-6-[propyl(2-thiophen-2-ylethyl)amino]-5,6,7,8-tetrahydronaphthalen-1-ol.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Rotigotine, (+)-

XLogP
4.2657
TPSA (Topological Polar Surface Area)
23.47
Hydrogen Bond Donors
1
Hydrogen Bond Acceptors
3
Rotatable Bonds
6
Heavy Atoms
22
Complexity
593.4876
Exact Mass
315.16568
Monoisotopic Mass
315.16568
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Rotigotine, (+)-

The XLogP value of 4.2657 indicates that Rotigotine, (+)- is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 23.47 Ų, Rotigotine, (+)- exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Rotigotine, (+)- has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Rotigotine, (+)-?

The CAS number of Rotigotine, (+)- is 112835-48-0.

What is the molecular formula of Rotigotine, (+)-?

The molecular formula of Rotigotine, (+)- is C19H25NOS.

What is the molecular weight of Rotigotine, (+)-?

The molecular weight of Rotigotine, (+)- is 315.17 g/mol.

Where can I buy Rotigotine, (+)-?

You can request a quote for Rotigotine, (+)- directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Rotigotine, (+)-?

Yes, KEHONG BIO provides custom synthesis services for Rotigotine, (+)- and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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