Spiro(pyrrolidine-3,2'(1'H)quinazolin)-5-one, 6'-chloro-4'-(2-fluorophenyl)-
TL;DR: Spiro(pyrrolidine-3,2'(1'H)quinazolin)-5-one, 6'-chloro-4'-(2-fluorophenyl)- (CAS 112634-58-9) is a chemical compound with molecular formula C17H13ClFN3O and molecular weight 329.07 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
6-chloro-4-(2-fluorophenyl)spiro[1H-quinazoline-2,4'-pyrrolidine]-2'-one
Also Known As: 6'-Chloro-4'-(2-fluorophenyl)spiro(pyrrolidine-3,2'(1'H)-quinazolin)-5-one, Spiro(pyrrolidine-3,2'(1'H)quinazolin)-5-one, 6'-chloro-4'-(2-fluorophenyl)-, 6-chloro-4-(2-fluorophenyl)spiro[1H-quinazoline-2,4'-pyrrolidine]-2'-one, Spiro[pyrrolidine-3,2'(1'H)-quinazolin]-5-one, 6'-chloro-4'-(2-fluorophenyl)-, 6'-Chloro-4'-(2-fluorophenyl)-2,4-dihydro-1'H-spiro[pyrrole-3,2'-quinazolin]-5-ol
| Molecular Formula | C17H13ClFN3O |
|---|---|
| Molecular Weight | 329.07 g/mol |
| LogP | 2.9582 |
| Topological Polar Surface Area | 53.49 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 1 |
| Exact Mass | 329.07312 |
| Heavy Atoms | 23 |
| Complexity | 851.4822 |
Chemical Identifiers
| CAS Number | 112634-58-9 |
|---|---|
| SMILES | C1C(=O)NCC12NC3=C(C=C(C=C3)Cl)C(=N2)C4=CC=CC=C4F |
Product Overview
Spiro(pyrrolidine-3,2'(1'H)quinazolin)-5-one, 6'-chloro-4'-(2-fluorophenyl)- (CAS 112634-58-9), with molecular formula C17H13ClFN3O and molecular weight 329.07 g/mol. IUPAC: 6-chloro-4-(2-fluorophenyl)spiro[1H-quinazoline-2,4'-pyrrolidine]-2'-one.
Chemical Property Profile of Spiro(pyrrolidine-3,2'(1'H)quinazolin)-5-one, 6'-chloro-4'-(2-fluorophenyl)-
Property Insights of Spiro(pyrrolidine-3,2'(1'H)quinazolin)-5-one, 6'-chloro-4'-(2-fluorophenyl)-
The XLogP value of 2.9582 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Spiro(pyrrolidine-3,2'(1'H)quinazolin)-5-one, 6'-chloro-4'-(2-fluorophenyl)-. With a topological polar surface area (TPSA) of 53.49 Ų, Spiro(pyrrolidine-3,2'(1'H)quinazolin)-5-one, 6'-chloro-4'-(2-fluorophenyl)- exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Spiro(pyrrolidine-3,2'(1'H)quinazolin)-5-one, 6'-chloro-4'-(2-fluorophenyl)- has 2 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Spiro(pyrrolidine-3,2'(1'H)quinazolin)-5-one, 6'-chloro-4'-(2-fluorophenyl)-?
The CAS number of Spiro(pyrrolidine-3,2'(1'H)quinazolin)-5-one, 6'-chloro-4'-(2-fluorophenyl)- is 112634-58-9.
What is the molecular formula of Spiro(pyrrolidine-3,2'(1'H)quinazolin)-5-one, 6'-chloro-4'-(2-fluorophenyl)-?
The molecular formula of Spiro(pyrrolidine-3,2'(1'H)quinazolin)-5-one, 6'-chloro-4'-(2-fluorophenyl)- is C17H13ClFN3O.
What is the molecular weight of Spiro(pyrrolidine-3,2'(1'H)quinazolin)-5-one, 6'-chloro-4'-(2-fluorophenyl)-?
The molecular weight of Spiro(pyrrolidine-3,2'(1'H)quinazolin)-5-one, 6'-chloro-4'-(2-fluorophenyl)- is 329.07 g/mol.
Where can I buy Spiro(pyrrolidine-3,2'(1'H)quinazolin)-5-one, 6'-chloro-4'-(2-fluorophenyl)-?
You can request a quote for Spiro(pyrrolidine-3,2'(1'H)quinazolin)-5-one, 6'-chloro-4'-(2-fluorophenyl)- directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Spiro(pyrrolidine-3,2'(1'H)quinazolin)-5-one, 6'-chloro-4'-(2-fluorophenyl)-?
Yes, KEHONG BIO provides custom synthesis services for Spiro(pyrrolidine-3,2'(1'H)quinazolin)-5-one, 6'-chloro-4'-(2-fluorophenyl)- and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.