N-(2-氟-4-羟基苯基)乙酰胺
TL;DR: N-(2-氟-4-羟基苯基)乙酰胺 (CAS 112523-75-8) is a chemical compound with molecular formula C8H8FNO2 and molecular weight 169.05 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-(2-氟-4-羟基苯基)乙酰胺
N-(2-fluoro-4-hydroxyphenyl)acetamide
Also Known As: n-(2-fluoro-4-hydroxyphenyl)acetamide, 4-Acetamido-3-fluorophenol, Regorafenib Impurity 58, Regorafenib Impurity 116, 4-acetylamino-3fluorophenol
| Molecular Formula | C8H8FNO2 |
|---|---|
| Molecular Weight | 169.05 g/mol |
| LogP | 0.9 |
| Topological Polar Surface Area | 49.3 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 1 |
| Exact Mass | 169.05391 |
| Heavy Atoms | 12 |
| Complexity | 174.0 |
Chemical Identifiers
| CAS Number | 112523-75-8 |
|---|---|
| SMILES | CC(=O)NC1=C(C=C(C=C1)O)F |
| InChIKey | BYKUYCWZSGDEFL-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 4 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
N-(2-氟-4-羟基苯基)乙酰胺 (CAS 112523-75-8), with molecular formula C8H8FNO2 and molecular weight 169.05 g/mol. IUPAC: N-(2-fluoro-4-hydroxyphenyl)acetamide.
Chemical Property Profile of N-(2-氟-4-羟基苯基)乙酰胺
Property Insights of N-(2-氟-4-羟基苯基)乙酰胺
The XLogP value of 0.9 suggests moderate lipophilicity, balancing water solubility and membrane permeability for N-(2-氟-4-羟基苯基)乙酰胺. With a topological polar surface area (TPSA) of 49.3 Ų, N-(2-氟-4-羟基苯基)乙酰胺 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, N-(2-氟-4-羟基苯基)乙酰胺 has 2 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of N-(2-氟-4-羟基苯基)乙酰胺?
The CAS number of N-(2-氟-4-羟基苯基)乙酰胺 is 112523-75-8.
What is the molecular formula of N-(2-氟-4-羟基苯基)乙酰胺?
The molecular formula of N-(2-氟-4-羟基苯基)乙酰胺 is C8H8FNO2.
What is the molecular weight of N-(2-氟-4-羟基苯基)乙酰胺?
The molecular weight of N-(2-氟-4-羟基苯基)乙酰胺 is 169.05 g/mol.
Where can I buy N-(2-氟-4-羟基苯基)乙酰胺?
You can request a quote for N-(2-氟-4-羟基苯基)乙酰胺 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for N-(2-氟-4-羟基苯基)乙酰胺?
Yes, KEHONG BIO provides custom synthesis services for N-(2-氟-4-羟基苯基)乙酰胺 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.