Gadobutrol Impurity 3 structure

Gadobutrol Impurity 3

TL;DR: Gadobutrol Impurity 3 (CAS 112188-16-6) is a chemical compound with molecular formula C14H23GdN4O6 and molecular weight 501.09 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

2-[4,7-bis(carboxylatomethyl)-1,4,7,10-tetrazacyclododec-1-yl]acetate;gadolinium(3+)

Also Known As: Gadobutrol Impurity 3, Gadobutrol EP Impurity C, gadoteridol Related Comp, Gd-DO3A, Gadoteridol Related Compound B

CAS: 112188-16-6
Molecular Formula C14H23GdN4O6
Molecular Weight 501.09 g/mol
LogP -6.2547
Topological Polar Surface Area 142.0 Ų
Hydrogen Bond Donors 1
Hydrogen Bond Acceptors 10
Rotatable Bonds 3
Exact Mass 501.08588
Heavy Atoms 25
Complexity 387.0

Chemical Identifiers

CAS Number 112188-16-6
SMILES C1CN(CCN(CCN(CCN1)CC(=O)[O-])CC(=O)[O-])CC(=O)[O-].[Gd+3]
InChIKey SGPXHPCSEYUXPA-UHFFFAOYSA-K

Patent-Derived Application Labels

Derived from 3 IPC patent classification(s) across the SureChEMBL global patent database.

Organometallic Reagents (1 patents) Peptides & Amino Acids (8 patents) Pharmaceutical Intermediates (12 patents)

Product Overview

Gadobutrol Impurity 3 (CAS 112188-16-6), with molecular formula C14H23GdN4O6 and molecular weight 501.09 g/mol. IUPAC: 2-[4,7-bis(carboxylatomethyl)-1,4,7,10-tetrazacyclododec-1-yl]acetate;gadolinium(3+).

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Gadobutrol Impurity 3

XLogP
-6.2547
TPSA (Topological Polar Surface Area)
142.0
Hydrogen Bond Donors
1
Hydrogen Bond Acceptors
10
Rotatable Bonds
3
Heavy Atoms
25
Complexity
387.0
Exact Mass
501.08588
Monoisotopic Mass
501.08588
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Gadobutrol Impurity 3

The XLogP value of -6.2547 indicates that Gadobutrol Impurity 3 is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 142.0 Ų indicates high polarity, suggesting Gadobutrol Impurity 3 may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Gadobutrol Impurity 3 has 1 hydrogen bond donor(s) and 10 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Gadobutrol Impurity 3?

The CAS number of Gadobutrol Impurity 3 is 112188-16-6.

What is the molecular formula of Gadobutrol Impurity 3?

The molecular formula of Gadobutrol Impurity 3 is C14H23GdN4O6.

What is the molecular weight of Gadobutrol Impurity 3?

The molecular weight of Gadobutrol Impurity 3 is 501.09 g/mol.

Where can I buy Gadobutrol Impurity 3?

You can request a quote for Gadobutrol Impurity 3 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Gadobutrol Impurity 3?

Yes, KEHONG BIO provides custom synthesis services for Gadobutrol Impurity 3 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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